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Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling.
Weber EW, Parker KR, Sotillo E, Lynn RC, Anbunathan H, Lattin J, Good Z, Belk JA, Daniel B, Klysz D, Malipatlolla M, Xu P, Bashti M, Heitzeneder S, Labanieh L, Vandris P, Majzner RG, Qi Y, Sandor K, Chen LC, Prabhu S, Gentles AJ, Wandless TJ, Satpathy AT, Chang HY, Mackall CL. Weber EW, et al. Among authors: wandless tj. Science. 2021 Apr 2;372(6537):eaba1786. doi: 10.1126/science.aba1786. Science. 2021. PMID: 33795428 Free PMC article.
Destabilizing domains derived from the human estrogen receptor.
Miyazaki Y, Imoto H, Chen LC, Wandless TJ. Miyazaki Y, et al. Among authors: wandless tj. J Am Chem Soc. 2012 Mar 7;134(9):3942-5. doi: 10.1021/ja209933r. Epub 2012 Feb 22. J Am Chem Soc. 2012. PMID: 22332638 Free PMC article.
Regulating protein stability in mammalian cells using small molecules.
Hagan EL, Banaszynski LA, Chen LC, Maynard-Smith LA, Wandless TJ. Hagan EL, et al. Among authors: wandless tj. Cold Spring Harb Protoc. 2009 Mar;2009(3):pdb.prot5172. doi: 10.1101/pdb.prot5172. Cold Spring Harb Protoc. 2009. PMID: 20147107 Free PMC article. No abstract available.
Recent progress with FKBP-derived destabilizing domains.
Chu BW, Banaszynski LA, Chen LC, Wandless TJ. Chu BW, et al. Among authors: wandless tj. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5941-4. doi: 10.1016/j.bmcl.2008.09.043. Epub 2008 Sep 12. Bioorg Med Chem Lett. 2008. PMID: 18815033 Free PMC article.
A cAMP Sensor Based on Ligand-Dependent Protein Stabilization.
Sidoli M, Chen LC, Lu AJ, Wandless TJ, Talbot WS. Sidoli M, et al. Among authors: wandless tj. ACS Chem Biol. 2022 Aug 19;17(8):2024-2030. doi: 10.1021/acschembio.2c00333. Epub 2022 Jul 15. ACS Chem Biol. 2022. PMID: 35839076 Free PMC article.
67 results