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Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling.
Weber EW, Parker KR, Sotillo E, Lynn RC, Anbunathan H, Lattin J, Good Z, Belk JA, Daniel B, Klysz D, Malipatlolla M, Xu P, Bashti M, Heitzeneder S, Labanieh L, Vandris P, Majzner RG, Qi Y, Sandor K, Chen LC, Prabhu S, Gentles AJ, Wandless TJ, Satpathy AT, Chang HY, Mackall CL. Weber EW, et al. Among authors: daniel b. Science. 2021 Apr 2;372(6537):eaba1786. doi: 10.1126/science.aba1786. Science. 2021. PMID: 33795428 Free PMC article.
Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2.
Nielsen SCA, Yang F, Jackson KJL, Hoh RA, Röltgen K, Stevens B, Lee JY, Rustagi A, Rogers AJ, Powell AE, Najeeb J, Otrelo-Cardoso AR, Yost KE, Daniel B, Chang HY, Satpathy AT, Jardetzky TS, Kim PS, Wang TT, Pinsky BA, Blish CA, Boyd SD. Nielsen SCA, et al. Among authors: daniel b. bioRxiv [Preprint]. 2020 Jul 9:2020.07.08.194456. doi: 10.1101/2020.07.08.194456. bioRxiv. 2020. Update in: Cell Host Microbe. 2020 Oct 7;28(4):516-525.e5. doi: 10.1016/j.chom.2020.09.002. PMID: 32676593 Free PMC article. Updated. Preprint.
Human B Cell Clonal Expansion and Convergent Antibody Responses to SARS-CoV-2.
Nielsen SCA, Yang F, Jackson KJL, Hoh RA, Röltgen K, Jean GH, Stevens BA, Lee JY, Rustagi A, Rogers AJ, Powell AE, Hunter M, Najeeb J, Otrelo-Cardoso AR, Yost KE, Daniel B, Nadeau KC, Chang HY, Satpathy AT, Jardetzky TS, Kim PS, Wang TT, Pinsky BA, Blish CA, Boyd SD. Nielsen SCA, et al. Among authors: daniel b. Cell Host Microbe. 2020 Oct 7;28(4):516-525.e5. doi: 10.1016/j.chom.2020.09.002. Epub 2020 Sep 3. Cell Host Microbe. 2020. PMID: 32941787 Free PMC article.
Epigenetic regulation of T cell exhaustion.
Belk JA, Daniel B, Satpathy AT. Belk JA, et al. Among authors: daniel b. Nat Immunol. 2022 Jun;23(6):848-860. doi: 10.1038/s41590-022-01224-z. Epub 2022 May 27. Nat Immunol. 2022. PMID: 35624210 Free PMC article. Review.
Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence.
Belk JA, Yao W, Ly N, Freitas KA, Chen YT, Shi Q, Valencia AM, Shifrut E, Kale N, Yost KE, Duffy CV, Daniel B, Hwee MA, Miao Z, Ashworth A, Mackall CL, Marson A, Carnevale J, Vardhana SA, Satpathy AT. Belk JA, et al. Among authors: daniel b. Cancer Cell. 2022 Jul 11;40(7):768-786.e7. doi: 10.1016/j.ccell.2022.06.001. Epub 2022 Jun 23. Cancer Cell. 2022. PMID: 35750052 Free PMC article.
RASA2 ablation in T cells boosts antigen sensitivity and long-term function.
Carnevale J, Shifrut E, Kale N, Nyberg WA, Blaeschke F, Chen YY, Li Z, Bapat SP, Diolaiti ME, O'Leary P, Vedova S, Belk J, Daniel B, Roth TL, Bachl S, Anido AA, Prinzing B, Ibañez-Vega J, Lange S, Haydar D, Luetke-Eversloh M, Born-Bony M, Hegde B, Kogan S, Feuchtinger T, Okada H, Satpathy AT, Shannon K, Gottschalk S, Eyquem J, Krenciute G, Ashworth A, Marson A. Carnevale J, et al. Among authors: daniel b. Nature. 2022 Sep;609(7925):174-182. doi: 10.1038/s41586-022-05126-w. Epub 2022 Aug 24. Nature. 2022. PMID: 36002574 Free PMC article.
667 results