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Oxaprozin Analogues as Selective RXR Agonists with Superior Properties and Pharmacokinetics.
J Med Chem. 2021 Apr 22;64(8):5123-5136. doi: 10.1021/acs.jmedchem.1c00235. Epub 2021 Apr 1.
J Med Chem. 2021.
PMID: 33793232
Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain.
Kramer JS, Woltersdorf S, Duflot T, Hiesinger K, Lillich FF, Knöll F, Wittmann SK, Klingler FM, Brunst S, Chaikuad A, Morisseau C, Hammock BD, Buccellati C, Sala A, Rovati GE, Leuillier M, Fraineau S, Rondeaux J, Hernandez-Olmos V, Heering J, Merk D, Pogoryelov D, Steinhilber D, Knapp S, Bellien J, Proschak E.
Kramer JS, et al. Among authors: woltersdorf s.
J Med Chem. 2019 Sep 26;62(18):8443-8460. doi: 10.1021/acs.jmedchem.9b00445. Epub 2019 Sep 17.
J Med Chem. 2019.
PMID: 31436984
Free PMC article.
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Characterization of the molecular mechanism of 5-lipoxygenase inhibition by 2-aminothiazoles.
Kretschmer SB, Woltersdorf S, Vogt D, Lillich FF, Rühl M, Karas M, Maucher IV, Roos J, Häfner AK, Kaiser A, Wurglics M, Schubert-Zsilavecz M, Angioni C, Geisslinger G, Stark H, Steinhilber D, Hofmann B.
Kretschmer SB, et al. Among authors: woltersdorf s.
Biochem Pharmacol. 2017 Jan 1;123:52-62. doi: 10.1016/j.bcp.2016.09.021. Epub 2016 Sep 23.
Biochem Pharmacol. 2017.
PMID: 27671344
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Development of novel aminothiazole-comprising 5-LO inhibitors.
M Kretschmer SB, Woltersdorf S, Rödl CB, Vogt D, Häfner AK, Steinhilber D, Stark H, Hofmann B.
M Kretschmer SB, et al. Among authors: woltersdorf s.
Future Med Chem. 2016;8(2):149-64. doi: 10.4155/fmc.15.174. Epub 2016 Jan 29.
Future Med Chem. 2016.
PMID: 26824797
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