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Page 1
Accelerated RNA detection using tandem CRISPR nucleases.
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, de León Derby MD, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim SE, Dugan EJ; IGI Testing Consortium; Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA. Liu TY, et al. Among authors: doudna ja. medRxiv [Preprint]. 2021 Mar 24:2021.03.19.21253328. doi: 10.1101/2021.03.19.21253328. medRxiv. 2021. Update in: Nat Chem Biol. 2021 Sep;17(9):982-988. doi: 10.1038/s41589-021-00842-2. PMID: 33791736 Free PMC article. Updated. Preprint.
Structures of the CRISPR genome integration complex.
Wright AV, Liu JJ, Knott GJ, Doxzen KW, Nogales E, Doudna JA. Wright AV, et al. Among authors: doudna ja. Science. 2017 Sep 15;357(6356):1113-1118. doi: 10.1126/science.aao0679. Epub 2017 Jul 20. Science. 2017. PMID: 28729350 Free PMC article.
A Broad-Spectrum Inhibitor of CRISPR-Cas9.
Harrington LB, Doxzen KW, Ma E, Liu JJ, Knott GJ, Edraki A, Garcia B, Amrani N, Chen JS, Cofsky JC, Kranzusch PJ, Sontheimer EJ, Davidson AR, Maxwell KL, Doudna JA. Harrington LB, et al. Among authors: doudna ja. Cell. 2017 Sep 7;170(6):1224-1233.e15. doi: 10.1016/j.cell.2017.07.037. Epub 2017 Aug 24. Cell. 2017. PMID: 28844692 Free PMC article.
Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.
Knott GJ, East-Seletsky A, Cofsky JC, Holton JM, Charles E, O'Connell MR, Doudna JA. Knott GJ, et al. Among authors: doudna ja. Nat Struct Mol Biol. 2017 Oct;24(10):825-833. doi: 10.1038/nsmb.3466. Epub 2017 Sep 11. Nat Struct Mol Biol. 2017. PMID: 28892041 Free PMC article.
CRISPR-Cas guides the future of genetic engineering.
Knott GJ, Doudna JA. Knott GJ, et al. Among authors: doudna ja. Science. 2018 Aug 31;361(6405):866-869. doi: 10.1126/science.aat5011. Science. 2018. PMID: 30166482 Free PMC article. Review.
388 results