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A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response.
Leibel SL, McVicar RN, Murad R, Kwong EM, Clark AE, Alvarado A, Grimmig BA, Nuryyev R, Young RE, Lee JC, Peng W, Zhu YP, Griffis E, Nowell CJ, James B, Alarcon S, Malhotra A, Gearing LJ, Hertzog PJ, Galapate CM, Galenkamp KMO, Commisso C, Smith DM, Sun X, Carlin AF, Sidman RL, Croker BA, Snyder EY. Leibel SL, et al. Among authors: nowell cj. Proc Natl Acad Sci U S A. 2024 Jul 23;121(30):e2408109121. doi: 10.1073/pnas.2408109121. Epub 2024 Jul 19. Proc Natl Acad Sci U S A. 2024. PMID: 39028694 Free PMC article.
TRPV4 is expressed by enteric glia and muscularis macrophages of the colon but does not play a prominent role in colonic motility.
Rajasekhar P, Carbone SE, Johnston ST, Nowell CJ, Wiklendt L, Crampin EJ, She Y, DiCello JJ, Saito A, Sorensen L, Nguyen T, Lee KM, Hamilton JA, King SK, Eriksson EM, Spencer NJ, Gulbransen BD, Veldhuis NA, Poole DP. Rajasekhar P, et al. Among authors: nowell cj. bioRxiv [Preprint]. 2024 Jan 11:2024.01.09.574831. doi: 10.1101/2024.01.09.574831. bioRxiv. 2024. PMID: 38260314 Free PMC article. Preprint.
NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils.
Zhu YP, Speir M, Tan Z, Lee JC, Nowell CJ, Chen AA, Amatullah H, Salinger AJ, Huang CJ, Wu G, Peng W, Askari K, Griffis E, Ghassemian M, Santini J, Gerlic M, Kiosses WB, Catz SD, Hoffman HM, Greco KF, Weller E, Thompson PR, Wong LP, Sadreyev R, Jeffrey KL, Croker BA. Zhu YP, et al. Among authors: nowell cj. Sci Adv. 2023 Dec 22;9(51):eadj1397. doi: 10.1126/sciadv.adj1397. Epub 2023 Dec 20. Sci Adv. 2023. PMID: 38117877 Free PMC article.
103 results