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Metformin ameliorates the severity of experimental Alport syndrome.
Omachi K, Kaseda S, Yokota T, Kamura M, Teramoto K, Kuwazuru J, Kojima H, Nohara H, Koyama K, Ohtsuki S, Misumi S, Takeo T, Nakagata N, Li JD, Shuto T, Suico MA, Miner JH, Kai H. Omachi K, et al. Among authors: koyama k. Sci Rep. 2021 Mar 29;11(1):7053. doi: 10.1038/s41598-021-86109-1. Sci Rep. 2021. PMID: 33782421 Free PMC article.
Podocyte p53 Limits the Severity of Experimental Alport Syndrome.
Fukuda R, Suico MA, Kai Y, Omachi K, Motomura K, Koga T, Komohara Y, Koyama K, Yokota T, Taura M, Shuto T, Kai H. Fukuda R, et al. Among authors: koyama k. J Am Soc Nephrol. 2016 Jan;27(1):144-57. doi: 10.1681/ASN.2014111109. Epub 2015 May 12. J Am Soc Nephrol. 2016. PMID: 25967122 Free PMC article.
A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome.
Omachi K, Kamura M, Teramoto K, Kojima H, Yokota T, Kaseda S, Kuwazuru J, Fukuda R, Koyama K, Matsuyama S, Motomura K, Shuto T, Suico MA, Kai H. Omachi K, et al. Among authors: koyama k. Cell Chem Biol. 2018 May 17;25(5):634-643.e4. doi: 10.1016/j.chembiol.2018.02.003. Epub 2018 Mar 8. Cell Chem Biol. 2018. PMID: 29526710 Free article.
Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury.
Koga T, Suico MA, Shimasaki S, Watanabe E, Kai Y, Koyama K, Omachi K, Morino-Koga S, Sato T, Shuto T, Mori K, Hino S, Nakao M, Kai H. Koga T, et al. Among authors: koyama k. J Biol Chem. 2015 Dec 18;290(51):30366-74. doi: 10.1074/jbc.M115.664169. Epub 2015 Oct 23. J Biol Chem. 2015. PMID: 26499802 Free PMC article.
Rb/E2F1 regulates the innate immune receptor Toll-like receptor 3 in epithelial cells.
Taura M, Suico MA, Koyama K, Komatsu K, Miyakita R, Matsumoto C, Kudo E, Kariya R, Goto H, Kitajima S, Takahashi C, Shuto T, Nakao M, Okada S, Kai H. Taura M, et al. Among authors: koyama k. Mol Cell Biol. 2012 Apr;32(8):1581-90. doi: 10.1128/MCB.06454-11. Epub 2012 Feb 6. Mol Cell Biol. 2012. PMID: 22310660 Free PMC article.
1,746 results