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Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation.
Deng X, Garcia-Knight MA, Khalid MM, Servellita V, Wang C, Morris MK, Sotomayor-González A, Glasner DR, Reyes KR, Gliwa AS, Reddy NP, Martin CSS, Federman S, Cheng J, Balcerek J, Taylor J, Streithorst JA, Miller S, Kumar GR, Sreekumar B, Chen PY, Schulze-Gahmen U, Taha TY, Hayashi J, Simoneau CR, McMahon S, Lidsky PV, Xiao Y, Hemarajata P, Green NM, Espinosa A, Kath C, Haw M, Bell J, Hacker JK, Hanson C, Wadford DA, Anaya C, Ferguson D, Lareau LF, Frankino PA, Shivram H, Wyman SK, Ott M, Andino R, Chiu CY. Deng X, et al. Among authors: ott m. medRxiv [Preprint]. 2021 Mar 9:2021.03.07.21252647. doi: 10.1101/2021.03.07.21252647. medRxiv. 2021. Update in: Cell. 2021 Jun 24;184(13):3426-3437.e8. doi: 10.1016/j.cell.2021.04.025. PMID: 33758899 Free PMC article. Updated. Preprint.
Accelerated RNA detection using tandem CRISPR nucleases.
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, de León Derby MD, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim SE, Dugan EJ; IGI Testing Consortium; Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA. Liu TY, et al. Among authors: ott m. medRxiv [Preprint]. 2021 Mar 24:2021.03.19.21253328. doi: 10.1101/2021.03.19.21253328. medRxiv. 2021. Update in: Nat Chem Biol. 2021 Sep;17(9):982-988. doi: 10.1038/s41589-021-00842-2. PMID: 33791736 Free PMC article. Updated. Preprint.
Sentinel cells enable genetic detection of SARS-CoV-2 Spike protein.
Weinberg ZY, Hilburger CE, Kim M, Cao L, Khalid M, Elmes S, Diwanji D, Hernandez E, Lopez J, Schaefer K, Smith AM, Zhou F; QCRG Structural Biology Consortium; Kumar GR, Ott M, Baker D, El-Samad H. Weinberg ZY, et al. Among authors: ott m. bioRxiv [Preprint]. 2021 Apr 20:2021.04.20.440678. doi: 10.1101/2021.04.20.440678. bioRxiv. 2021. PMID: 33907743 Free PMC article. Preprint.
SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator.
Hysenaj L, Little S, Kulhanek K, Gbenedio OM, Rodriguez L, Shen A, Lone JC, Lupin-Jimenez LC, Bonser LR, Serwas NK, Bahl K, Mick E, Li JZ, Ding VW, Matsumoto S, Maishan M, Simoneau C, Fragiadakis G, Jablons DM, Langelier CR, Matthay M, Ott M, Krummel M, Combes AJ, Sil A, Erle DJ, Kratz JR, Roose JP. Hysenaj L, et al. Among authors: ott m. bioRxiv [Preprint]. 2021 Jun 2:2021.06.01.446640. doi: 10.1101/2021.06.01.446640. bioRxiv. 2021. PMID: 34100012 Free PMC article. Preprint.
Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles.
Syed AM, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Spraggon L, Taha TY, Tabata T, Chen IP, Ott M, Doudna JA. Syed AM, et al. Among authors: ott m. medRxiv [Preprint]. 2022 Jan 2:2021.12.20.21268048. doi: 10.1101/2021.12.20.21268048. medRxiv. 2022. Update in: Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2200592119. doi: 10.1073/pnas.2200592119. PMID: 34981067 Free PMC article. Updated. Preprint.
SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.
Walter M, Chen IP, Vallejo-Gracia A, Kim IJ, Bielska O, Lam VL, Hayashi JM, Cruz A, Shah S, Gross JD, Krogan NJ, Schilling B, Ott M, Verdin E. Walter M, et al. Among authors: ott m. bioRxiv [Preprint]. 2022 Jan 5:2022.01.04.474979. doi: 10.1101/2022.01.04.474979. bioRxiv. 2022. Update in: PLoS Pathog. 2022 Sep 12;18(9):e1010811. doi: 10.1371/journal.ppat.1010811. PMID: 35018374 Free PMC article. Updated. Preprint.
Immediate myeloid depot for SARS-CoV-2 in the human lung.
Magnen M, You R, Rao AA, Davis RT, Rodriguez L, Simoneau CR, Hysenaj L, Hu KH; UCSF COMET Consortium; Love C, Woodruff PG, Erle DJ, Hendrickson CM, Calfee CS, Matthay MA, Roose JP, Sil A, Ott M, Langelier CR, Krummel MF, Looney MR. Magnen M, et al. Among authors: ott m. bioRxiv [Preprint]. 2022 May 11:2022.04.28.489942. doi: 10.1101/2022.04.28.489942. bioRxiv. 2022. Update in: Sci Adv. 2024 Aug 2;10(31):eadm8836. doi: 10.1126/sciadv.adm8836. PMID: 35592107 Free PMC article. Updated. Preprint.
Immediate myeloid depot for SARS-CoV-2 in the human lung.
Magnen M, You R, Rao AA, Davis RT, Rodriguez L, Simoneau CR, Hysenaj L, Hu KH; UCSF COMET Consortium; Love C, Woodruff PG, Erle DJ, Hendrickson CM, Calfee CS, Matthay MA, Roose JP, Sil A, Ott M, Langelier CR, Krummel MF, Looney MR. Magnen M, et al. Among authors: ott m. Res Sq [Preprint]. 2022 May 17:rs.3.rs-1639631. doi: 10.21203/rs.3.rs-1639631/v1. Res Sq. 2022. Update in: Sci Adv. 2024 Aug 2;10(31):eadm8836. doi: 10.1126/sciadv.adm8836. PMID: 35611333 Free PMC article. Updated. Preprint.
Mild SARS-CoV-2 infection results in long-lasting microbiota instability.
Upadhyay V, Suryawanshi R, Tasoff P, McCavitt-Malvido M, Kumar GR, Murray VW, Noecker C, Bisanz JE, Hswen Y, Ha C, Sreekumar B, Chen IP, Lynch SV, Ott M, Lee S, Turnbaugh PJ. Upadhyay V, et al. Among authors: ott m. bioRxiv [Preprint]. 2022 Dec 8:2022.12.07.519508. doi: 10.1101/2022.12.07.519508. bioRxiv. 2022. Update in: mBio. 2023 Aug 31;14(4):e0088923. doi: 10.1128/mbio.00889-23. PMID: 36523400 Free PMC article. Updated. Preprint.
1,273 results