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Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response.
Nguyen LC, Yang D, Nicolaescu V, Best TJ, Ohtsuki T, Chen SN, Friesen JB, Drayman N, Mohamed A, Dann C, Silva D, Gula H, Jones KA, Millis JM, Dickinson BC, Tay S, Oakes SA, Pauli GF, Meltzer DO, Randall G, Rosner MR. Nguyen LC, et al. Among authors: randall g. bioRxiv [Preprint]. 2021 Mar 10:2021.03.10.432967. doi: 10.1101/2021.03.10.432967. bioRxiv. 2021. Update in: Sci Adv. 2022 Feb 25;8(8):eabi6110. doi: 10.1126/sciadv.abi6110 PMID: 33758843 Free PMC article. Updated. Preprint.
Polymersomes decorated with SARS-CoV-2 spike protein receptor binding domain elicit robust humoral and cellular immunity.
Volpatti LR, Wallace RP, Cao S, Raczy MM, Wang R, Gray LT, Alpar AT, Briquez PS, Mitrousis N, Marchell TM, Sasso MS, Nguyen M, Mansurov A, Budina E, Solanki A, Watkins EA, Schnorenberg MR, Tremain AC, Reda JW, Nicolaescu V, Furlong K, Dvorkin S, Yu SS, Manicassamy B, LaBelle JL, Tirrell MV, Randall G, Kwissa M, Swartz MA, Hubbell JA. Volpatti LR, et al. Among authors: randall g. bioRxiv [Preprint]. 2021 Apr 8:2021.04.08.438884. doi: 10.1101/2021.04.08.438884. bioRxiv. 2021. Update in: ACS Cent Sci. 2021 Aug 25;7(8):1368-1380. doi: 10.1021/acscentsci.1c00596 PMID: 33851166 Free PMC article. Updated. Preprint.
A comprehensive SARS-CoV-2-human protein-protein interactome network identifies pathobiology and host-targeting therapies for COVID-19.
Zhou Y, Liu Y, Gupta S, Paramo MI, Hou Y, Mao C, Luo Y, Judd J, Wierbowski S, Bertolotti M, Nerkar M, Jehi L, Drayman N, Nicolaescu V, Gula H, Tay S, Randall G, Lis JT, Feschotte C, Erzurum SC, Cheng F, Yu H. Zhou Y, et al. Among authors: randall g. Res Sq [Preprint]. 2022 Jun 7:rs.3.rs-1354127. doi: 10.21203/rs.3.rs-1354127/v2. Res Sq. 2022. Update in: Nat Biotechnol. 2023 Jan;41(1):128-139. doi: 10.1038/s41587-022-01474-0 PMID: 35677070 Free PMC article. Updated. Preprint.
SARS-CoV-2 diverges from other betacoronaviruses in only partially activating the IRE1α/XBP1 ER stress pathway in human lung-derived cells.
Nguyen LC, Renner DM, Silva D, Yang D, Parenti N, Medina KM, Nicolaescu V, Gula H, Drayman N, Valdespino A, Mohamed A, Dann C, Wannemo K, Robinson-Mailman L, Gonzalez A, Stock L, Cao M, Qiao Z, Moellering RE, Tay S, Randall G, Beers MF, Rosner MR, Oakes SA, Weiss SR. Nguyen LC, et al. Among authors: randall g. bioRxiv [Preprint]. 2022 Jun 13:2021.12.30.474519. doi: 10.1101/2021.12.30.474519. bioRxiv. 2022. Update in: mBio. 2022 Oct 26;13(5):e0241522. doi: 10.1128/mbio.02415-22 PMID: 35821981 Free PMC article. Updated. Preprint.
Superiority of intranasal over systemic administration of bioengineered soluble ACE2 for survival and brain protection against SARS-CoV-2 infection.
Hassler L, Wysocki J, Ahrendsen JT, Ye M, Gelarden I, Nicolaescu V, Tomatsidou A, Gula H, Cianfarini C, Khurram N, Kanwar Y, Singer BD, Randall G, Missiakas D, Henkin J, Batlle D. Hassler L, et al. Among authors: randall g. bioRxiv [Preprint]. 2022 Dec 6:2022.12.05.519032. doi: 10.1101/2022.12.05.519032. bioRxiv. 2022. PMID: 36523403 Free PMC article. Preprint.
Soluble Angiotensin-Converting Enzyme 2 Protein Improves Survival and Lowers Viral Titers in Lethal Mouse Model of Severe Acute Respiratory Syndrome Coronavirus Type 2 Infection with the Delta Variant.
Cianfarini C, Hassler L, Wysocki J, Hassan A, Nicolaescu V, Elli D, Gula H, Ibrahim AM, Randall G, Henkin J, Batlle D. Cianfarini C, et al. Among authors: randall g. Cells. 2024 Jan 23;13(3):203. doi: 10.3390/cells13030203. Cells. 2024. PMID: 38334597 Free PMC article.
Novel antibody language model accelerates IgG screening and design for broad-spectrum antiviral therapy.
Almubarak HF, Tan W, Hoffmann AD, Sun Y, Wei J, El-Shennawy L, Squires JR, Dashzeveg NK, Simonton B, Jia Y, Iyer R, Xu Y, Nicolaescu V, Elli D, Randall GC, Schipma MJ, Swaminathan S, Ison MG, Liu H, Fang D, Shen Y. Almubarak HF, et al. Among authors: randall gc. bioRxiv [Preprint]. 2024 Aug 20:2024.03.01.582176. doi: 10.1101/2024.03.01.582176. bioRxiv. 2024. PMID: 38496411 Free PMC article. Preprint.
305 results