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Page 1
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection.
Wettstein L, Weil T, Conzelmann C, Müller JA, Groß R, Hirschenberger M, Seidel A, Klute S, Zech F, Prelli Bozzo C, Preising N, Fois G, Lochbaum R, Knaff PM, Mailänder V, Ständker L, Thal DR, Schumann C, Stenger S, Kleger A, Lochnit G, Mayer B, Ruiz-Blanco YB, Hoffmann M, Sparrer KMJ, Pöhlmann S, Sanchez-Garcia E, Kirchhoff F, Frick M, Münch J. Wettstein L, et al. Among authors: prelli bozzo c. Nat Commun. 2021 Mar 19;12(1):1726. doi: 10.1038/s41467-021-21972-0. Nat Commun. 2021. PMID: 33741941 Free PMC article.
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro.
Prelli Bozzo C, Nchioua R, Volcic M, Koepke L, Krüger J, Schütz D, Heller S, Stürzel CM, Kmiec D, Conzelmann C, Müller J, Zech F, Braun E, Groß R, Wettstein L, Weil T, Weiß J, Diofano F, Rodríguez Alfonso AA, Wiese S, Sauter D, Münch J, Goffinet C, Catanese A, Schön M, Boeckers TM, Stenger S, Sato K, Just S, Kleger A, Sparrer KMJ, Kirchhoff F. Prelli Bozzo C, et al. Nat Commun. 2021 Jul 28;12(1):4584. doi: 10.1038/s41467-021-24817-y. Nat Commun. 2021. PMID: 34321474 Free PMC article.
Spike residue 403 affects binding of coronavirus spikes to human ACE2.
Zech F, Schniertshauer D, Jung C, Herrmann A, Cordsmeier A, Xie Q, Nchioua R, Prelli Bozzo C, Volcic M, Koepke L, Müller JA, Krüger J, Heller S, Stenger S, Hoffmann M, Pöhlmann S, Kleger A, Jacob T, Conzelmann KK, Ensser A, Sparrer KMJ, Kirchhoff F. Zech F, et al. Among authors: prelli bozzo c. Nat Commun. 2021 Nov 25;12(1):6855. doi: 10.1038/s41467-021-27180-0. Nat Commun. 2021. PMID: 34824253 Free PMC article.
Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities.
Hayn M, Hirschenberger M, Koepke L, Nchioua R, Straub JH, Klute S, Hunszinger V, Zech F, Prelli Bozzo C, Aftab W, Christensen MH, Conzelmann C, Müller JA, Srinivasachar Badarinarayan S, Stürzel CM, Forne I, Stenger S, Conzelmann KK, Münch J, Schmidt FI, Sauter D, Imhof A, Kirchhoff F, Sparrer KMJ. Hayn M, et al. Among authors: prelli bozzo c. Cell Rep. 2021 May 18;35(7):109126. doi: 10.1016/j.celrep.2021.109126. Epub 2021 Apr 27. Cell Rep. 2021. PMID: 33974846 Free PMC article.
Antimicrobial Activity of Cyclic-Monomeric and Dimeric Derivatives of the Snail-Derived Peptide Cm-p5 against Viral and Multidrug-Resistant Bacterial Strains.
González-García M, Morales-Vicente F, Pico ED, Garay H, Rivera DG, Grieshober M, Raluca Olari L, Groß R, Conzelmann C, Krüger F, Zech F, Prelli Bozzo C, Müller JA, Zelikin A, Raber H, Kubiczek D, Rosenau F, Münch J, Stenger S, Spellerberg B, Franco OL, Rodriguez Alfonso AA, Ständker L, Otero-Gonzalez AJ. González-García M, et al. Among authors: prelli bozzo c. Biomolecules. 2021 May 17;11(5):745. doi: 10.3390/biom11050745. Biomolecules. 2021. PMID: 34067685 Free PMC article.
RINT1 Regulates SUMOylation and the DNA Damage Response to Preserve Cellular Homeostasis in Pancreatic Cancer.
Arnold F, Gout J, Wiese H, Weissinger SE, Roger E, Perkhofer L, Walter K, Scheible J, Prelli Bozzo C, Lechel A, Ettrich TJ, Azoitei N, Hao L, Fürstberger A, Kaminska EK, Sparrer KMJ, Rasche V, Wiese S, Kestler HA, Möller P, Seufferlein T, Frappart PO, Kleger A. Arnold F, et al. Among authors: prelli bozzo c. Cancer Res. 2021 Apr 1;81(7):1758-1774. doi: 10.1158/0008-5472.CAN-20-2633. Epub 2021 Feb 2. Cancer Res. 2021. PMID: 33531371
Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.
Bosso M, Prelli Bozzo C, Hotter D, Volcic M, Stürzel CM, Rammelt A, Ni Y, Urban S, Becker M, Schelhaas M, Wittmann S, Christensen MH, Schmidt FI, Gramberg T, Sparrer KMJ, Sauter D, Kirchhoff F. Bosso M, et al. Among authors: prelli bozzo c. PLoS Pathog. 2020 Aug 6;16(8):e1008752. doi: 10.1371/journal.ppat.1008752. eCollection 2020 Aug. PLoS Pathog. 2020. PMID: 32760121 Free PMC article.
12 results