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Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma.
Zhao X, Wang MY, Jiang H, Lwin T, Park PM, Gao J, Meads MB, Ren Y, Li T, Sun J, Fahmi NA, Singh S, Sehgal L, Wang X, Silva AS, Sotomayor EM, Shain KH, Cleveland JL, Wang M, Zhang W, Qi J, Shah BD, Tao J. Zhao X, et al. Among authors: wang my, wang x, wang m. Cell Rep. 2021 Mar 16;34(11):108870. doi: 10.1016/j.celrep.2021.108870. Cell Rep. 2021. PMID: 33730585 Free PMC article.
BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models.
Zhao X, Ren Y, Lawlor M, Shah BD, Park PMC, Lwin T, Wang X, Liu K, Wang M, Gao J, Li T, Xu M, Silva AS, Lee K, Zhang T, Koomen JM, Jiang H, Sudalagunta PR, Meads MB, Cheng F, Bi C, Fu K, Fan H, Dalton WS, Moscinski LC, Shain KH, Sotomayor EM, Wang GG, Gray NS, Cleveland JL, Qi J, Tao J. Zhao X, et al. Among authors: wang x, wang gg, wang m. Cancer Cell. 2019 May 13;35(5):752-766.e9. doi: 10.1016/j.ccell.2019.04.005. Cancer Cell. 2019. PMID: 31085176 Free PMC article.
Response and resistance to CDK12 inhibition in aggressive B-cell lymphomas.
Gao J, Wang MY, Ren Y, Lwin T, Li T, Yan JC, Sotomayor EM, Duckett DR, Shah BD, Shain KH, Zhao X, Tao J. Gao J, et al. Among authors: wang my. Haematologica. 2022 May 1;107(5):1119-1130. doi: 10.3324/haematol.2021.278743. Haematologica. 2022. PMID: 34162179 Free PMC article.
MCL1 as a therapeutic vulnerability in Burkitt lymphoma.
Yuan R, Wang MY, Bi C, Zhao X, Tao J. Yuan R, et al. Leukemia. 2023 Apr;37(4):934-937. doi: 10.1038/s41375-023-01827-x. Epub 2023 Feb 2. Leukemia. 2023. PMID: 36732564 No abstract available.
Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders.
Li YD, Ma MW, Hassan MM, Hunkeler M, Teng M, Puvar K, Lumpkin R, Sandoval B, Jin CY, Ficarro SB, Wang MY, Xu S, Groendyke BJ, Sigua LH, Tavares I, Zou C, Tsai JM, Park PMC, Yoon H, Majewski FC, Marto JA, Qi J, Nowak RP, Donovan KA, Słabicki M, Gray NS, Fischer ES, Ebert BL. Li YD, et al. Among authors: wang my. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528208. doi: 10.1101/2023.02.14.528208. bioRxiv. 2023. Update in: Nat Chem Biol. 2024 Jul 29. doi: 10.1038/s41589-024-01668-4. PMID: 36824856 Free PMC article. Updated. Preprint.
Template-assisted covalent modification underlies activity of covalent molecular glues.
Li YD, Ma MW, Hassan MM, Hunkeler M, Teng M, Puvar K, Rutter JC, Lumpkin RJ, Sandoval B, Jin CY, Schmoker AM, Ficarro SB, Cheong H, Metivier RJ, Wang MY, Xu S, Byun WS, Groendyke BJ, You I, Sigua LH, Tavares I, Zou C, Tsai JM, Park PMC, Yoon H, Majewski FC, Sperling HT, Marto JA, Qi J, Nowak RP, Donovan KA, Słabicki M, Gray NS, Fischer ES, Ebert BL. Li YD, et al. Among authors: wang my. Nat Chem Biol. 2024 Jul 29. doi: 10.1038/s41589-024-01668-4. Online ahead of print. Nat Chem Biol. 2024. PMID: 39075252
Exploration of the Tunability of BRD4 Degradation by DCAF16 Trans-labelling Covalent Glues.
Hassan MM, Li YD, Ma MW, Teng M, Byun WS, Puvar K, Lumpkin R, Sandoval B, Rutter JC, Jin CY, Wang MY, Xu S, Schmoker AM, Cheong H, Groendyke BJ, Qi J, Fischer ES, Ebert BL, Gray NS. Hassan MM, et al. Among authors: wang my. bioRxiv [Preprint]. 2023 Oct 10:2023.10.07.561308. doi: 10.1101/2023.10.07.561308. bioRxiv. 2023. Update in: Eur J Med Chem. 2024 Dec 5;279:116904. doi: 10.1016/j.ejmech.2024.116904. PMID: 37873358 Free PMC article. Updated. Preprint.
Exploration of the tunability of BRD4 degradation by DCAF16 trans-labelling covalent glues.
Hassan MM, Li YD, Ma MW, Teng M, Byun WS, Puvar K, Lumpkin R, Sandoval B, Rutter JC, Jin CY, Wang MY, Xu S, Schmoker AM, Cheong H, Groendyke BJ, Qi J, Fischer ES, Ebert BL, Gray NS. Hassan MM, et al. Among authors: wang my. Eur J Med Chem. 2024 Dec 5;279:116904. doi: 10.1016/j.ejmech.2024.116904. Epub 2024 Sep 24. Eur J Med Chem. 2024. PMID: 39341093 Free article.
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