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405 results

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Page 1
Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion.
Cockerill GS, Angell RM, Bedernjak A, Chuckowree I, Fraser I, Gascon-Simorte J, Gilman MSA, Good JAD, Harland R, Johnson SM, Ludes-Meyers JH, Littler E, Lumley J, Lunn G, Mathews N, McLellan JS, Paradowski M, Peeples ME, Scott C, Tait D, Taylor G, Thom M, Thomas E, Villalonga Barber C, Ward SE, Watterson D, Williams G, Young P, Powell K. Cockerill GS, et al. Among authors: lumley j. J Med Chem. 2021 Apr 8;64(7):3658-3676. doi: 10.1021/acs.jmedchem.0c01882. Epub 2021 Mar 17. J Med Chem. 2021. PMID: 33729773
1,4-benzodiazepines as inhibitors of respiratory syncytial virus. The identification of a clinical candidate.
Henderson EA, Alber DG, Baxter RC, Bithell SK, Budworth J, Carter MC, Chubb A, Cockerill GS, Dowdell VC, Fraser IJ, Harris RA, Keegan SJ, Kelsey RD, Lumley JA, Stables JN, Weerasekera N, Wilson LJ, Powell KL. Henderson EA, et al. Among authors: lumley ja. J Med Chem. 2007 Apr 5;50(7):1685-92. doi: 10.1021/jm060747l. Epub 2007 Mar 7. J Med Chem. 2007. PMID: 17341059
Molecule Ideation Using Matched Molecular Pairs.
Pal S, Pogány P, Lumley JA. Pal S, et al. Among authors: lumley ja. Methods Mol Biol. 2022;2390:503-521. doi: 10.1007/978-1-0716-1787-8_23. Methods Mol Biol. 2022. PMID: 34731485
A KNIME Workflow for Automated Structure Verification.
Lumley JA, Sharman G, Wilkin T, Hirst M, Cobas C, Goebel M. Lumley JA, et al. SLAS Discov. 2020 Sep;25(8):950-956. doi: 10.1177/2472555220907091. Epub 2020 Feb 21. SLAS Discov. 2020. PMID: 32081066 Free article.
Author Correction: Cutaneous T cell lymphoma atlas reveals malignant TH2 cells supported by a B cell-rich tumor microenvironment.
Li R, Strobl J, Poyner EFM, Balbaa A, Torabi F, Mazin PV, Chipampe NJ, Stephenson E, Ramírez-Suástegi C, Shanmugiah VBM, Gardner L, Olabi B, Coulthard R, Botting RA, Zila N, Prigmore E, Gopee NH, Chroscik MA, Kritikaki E, Engelbert J, Goh I, Chan HM, Johnson HF, Ellis J, Rowe V, Tun W, Reynolds G, Yang D, Foster AR, Gambardella L, Winheim E, Admane C, Rumney B, Steele L, Jardine L, Nenonen J, Pickard K, Lumley J, Hampton P, Hu S, Liu F, Liu X, Horsfall D, Basurto-Lozada D, Grimble L, Bacon CM, Weatherhead SC, Brauner H, Wang Y, Bai F, Reynolds NJ, Allen JE, Jonak C, Brunner PM, Teichmann SA, Haniffa M. Li R, et al. Among authors: lumley j. Nat Immunol. 2024 Dec 2. doi: 10.1038/s41590-024-02046-x. Online ahead of print. Nat Immunol. 2024. PMID: 39622949 No abstract available.
Cutaneous T cell lymphoma atlas reveals malignant TH2 cells supported by a B cell-rich tumor microenvironment.
Li R, Strobl J, Poyner EFM, Balbaa A, Torabi F, Mazin PV, Chipampe NJ, Stephenson E, Ramírez-Suástegi C, Shanmugiah VBM, Gardner L, Olabi B, Coulthard R, Botting RA, Zila N, Prigmore E, Gopee NH, Chroscik MA, Kritikaki E, Engelbert J, Goh I, Chan HM, Johnson HF, Ellis J, Rowe V, Tun W, Reynolds G, Yang D, Foster AR, Gambardella L, Winheim E, Admane C, Rumney B, Steele L, Jardine L, Nenonen J, Pickard K, Lumley J, Hampton P, Hu S, Liu F, Liu X, Horsfall D, Basurto-Lozada D, Grimble L, Bacon CM, Weatherhead SC, Brauner H, Wang Y, Bai F, Reynolds NJ, Allen JE, Jonak C, Brunner PM, Teichmann SA, Haniffa M. Li R, et al. Among authors: lumley j. Nat Immunol. 2024 Dec;25(12):2320-2330. doi: 10.1038/s41590-024-02018-1. Epub 2024 Nov 18. Nat Immunol. 2024. PMID: 39558094 Free PMC article.
A phase 4, open-label study to evaluate the safety and immunogenicity of DTaP5-HBV-IPV-Hib in children previously vaccinated with DTaP2-HBV-IPV-Hib or DTaP5-HBV-IPV-Hib (V419-016).
Guerra A, Costantino C, Martinon-Torres F, Westerholt S, Lambeth C, Chen Z, Lumley J, Marcek T, Johnson D, Wilck M. Guerra A, et al. Among authors: lumley j. Hum Vaccin Immunother. 2024 Dec 31;20(1):2310900. doi: 10.1080/21645515.2024.2310900. Epub 2024 Feb 8. Hum Vaccin Immunother. 2024. PMID: 38327239 Free PMC article. Clinical Trial.
Safety and Tolerability of V114 Pneumococcal Vaccine in Infants: A Phase 3 Study.
Banniettis N, Horn M, Sadarangani M, Patel SM, Greenberg D, Oberdorfer P, Klein NP, Rupp R, Dagan R, Richmond P, Lumley J, Zhou W, Shi Y, Tamms G, Feemster K, Lupinacci R, Musey L, Bickham K; V114-031 (PNEU-LINK) study group. Banniettis N, et al. Among authors: lumley j. Pediatrics. 2023 Jul 1;152(1):e2022060428. doi: 10.1542/peds.2022-060428. Pediatrics. 2023. PMID: 37309607 Clinical Trial.
405 results