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Elevated levels of mitochondrial CoQ10 induce ROS-mediated apoptosis in pancreatic cancer.
Dadali T, Diers AR, Kazerounian S, Muthuswamy SK, Awate P, Ng R, Mogre S, Spencer C, Krumova K, Rockwell HE, McDaniel J, Chen EY, Gao F, Diedrich KT, Vemulapalli V, Rodrigues LO, Akmaev VR, Thapa K, Hidalgo M, Bose A, Vishnudas VK, Moser AJ, Granger E, Kiebish MA, Gesta S, Narain NR, Sarangarajan R. Dadali T, et al. Among authors: sarangarajan r. Sci Rep. 2021 Mar 11;11(1):5749. doi: 10.1038/s41598-021-84852-z. Sci Rep. 2021. PMID: 33707480 Free PMC article.
High levels of ubidecarenone (oxidized CoQ10) delivered using a drug-lipid conjugate nanodispersion (BPM31510) differentially affect redox status and growth in malignant glioma versus non-tumor cells.
Sun J, Patel CB, Jang T, Merchant M, Chen C, Kazerounian S, Diers AR, Kiebish MA, Vishnudas VK, Gesta S, Sarangarajan R, Narain NR, Nagpal S, Recht L. Sun J, et al. Among authors: sarangarajan r. Sci Rep. 2020 Aug 17;10(1):13899. doi: 10.1038/s41598-020-70969-0. Sci Rep. 2020. PMID: 32807842 Free PMC article.
Chronic stress and antidepressant treatment alter purine metabolism and beta oxidation within mouse brain and serum.
Hamilton PJ, Chen EY, Tolstikov V, Peña CJ, Picone JA, Shah P, Panagopoulos K, Strat AN, Walker DM, Lorsch ZS, Robinson HL, Mervosh NL, Kiraly DD, Sarangarajan R, Narain NR, Kiebish MA, Nestler EJ. Hamilton PJ, et al. Among authors: sarangarajan r. Sci Rep. 2020 Oct 22;10(1):18134. doi: 10.1038/s41598-020-75114-5. Sci Rep. 2020. PMID: 33093530 Free PMC article.
Clinical utility of a serum biomarker panel in distinguishing prostate cancer from benign prostate hyperplasia.
Kiebish MA, Tekumalla P, Ravipaty S, Dobi A, Srivastava S, Wu W, Patil S, Friss T, Klotz A, Srinivasan A, Cullen J, Rosner IL, Ali A, Laszlo S, Petrovic M, Fleshner N, Garren J, Miller G, Mahaveer Chand N, Rodrigues LO, Granger E, Kellogg MD, Luan S, Diamandis E, Akmaev VR, Sarangarajan R, Bountra C, Freedland SJ, McLeod DG, Narain NR. Kiebish MA, et al. Among authors: sarangarajan r. Sci Rep. 2021 Jul 23;11(1):15052. doi: 10.1038/s41598-021-94438-4. Sci Rep. 2021. PMID: 34302010 Free PMC article.
Impact of hemolysis on multi-OMIC pancreatic biomarker discovery to derisk biomarker development in precision medicine studies.
Searfoss R, Shah P, Ofori-Mensa K, Bussberg V, Tolstikov V, Greenwood B, Li H, Richardson K, Miller GM, DeCicco C, Granger E, Rodrigues LO, Grund EM, Moser AJ, Sarangarajan R, Narain NR, Kiebish MA. Searfoss R, et al. Among authors: sarangarajan r. Sci Rep. 2022 Jan 24;12(1):1186. doi: 10.1038/s41598-022-05152-8. Sci Rep. 2022. PMID: 35075163 Free PMC article.
80 results