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Elevated levels of mitochondrial CoQ10 induce ROS-mediated apoptosis in pancreatic cancer.
Dadali T, Diers AR, Kazerounian S, Muthuswamy SK, Awate P, Ng R, Mogre S, Spencer C, Krumova K, Rockwell HE, McDaniel J, Chen EY, Gao F, Diedrich KT, Vemulapalli V, Rodrigues LO, Akmaev VR, Thapa K, Hidalgo M, Bose A, Vishnudas VK, Moser AJ, Granger E, Kiebish MA, Gesta S, Narain NR, Sarangarajan R. Dadali T, et al. Among authors: diers ar. Sci Rep. 2021 Mar 11;11(1):5749. doi: 10.1038/s41598-021-84852-z. Sci Rep. 2021. PMID: 33707480 Free PMC article.
High levels of ubidecarenone (oxidized CoQ10) delivered using a drug-lipid conjugate nanodispersion (BPM31510) differentially affect redox status and growth in malignant glioma versus non-tumor cells.
Sun J, Patel CB, Jang T, Merchant M, Chen C, Kazerounian S, Diers AR, Kiebish MA, Vishnudas VK, Gesta S, Sarangarajan R, Narain NR, Nagpal S, Recht L. Sun J, et al. Among authors: diers ar. Sci Rep. 2020 Aug 17;10(1):13899. doi: 10.1038/s41598-020-70969-0. Sci Rep. 2020. PMID: 32807842 Free PMC article.
Diablo ubiquitination analysis by sandwich immunoassay.
Guven A, Wu WS, Patil S, Gokul K, Tekumalla P, Sharma S, Diers A, Gesta S, Vishnudas V, Sarangarajan R, Kellogg MD, Narain NR, Kiebish MA. Guven A, et al. J Pharm Biomed Anal. 2019 Sep 5;173:40-46. doi: 10.1016/j.jpba.2019.05.005. Epub 2019 May 3. J Pharm Biomed Anal. 2019. PMID: 31108422
Identification of Filamin-A and -B as potential biomarkers for prostate cancer.
Narain NR, Diers AR, Lee A, Lao S, Chan JY, Schofield S, Andreazi J, Ouro-Djobo R, Jimenez JJ, Friss T, Tanna N, Dalvi A, Wang S, Bunch D, Sun Y, Wu W, Thapa K, Gesta S, Rodrigues LO, Akmaev VR, Vishnudas VK, Sarangarajan R. Narain NR, et al. Among authors: diers ar. Future Sci OA. 2016 Dec 22;3(1):FSO161. doi: 10.4155/fsoa-2016-0065. eCollection 2017 Mar. Future Sci OA. 2016. PMID: 28344825 Free PMC article.
A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms.
Vayalil PK, Oh JY, Zhou F, Diers AR, Smith MR, Golzarian H, Oliver PG, Smith RA, Murphy MP, Velu SE, Landar A. Vayalil PK, et al. Among authors: diers ar. PLoS One. 2015 Mar 18;10(3):e0120460. doi: 10.1371/journal.pone.0120460. eCollection 2015. PLoS One. 2015. PMID: 25785718 Free PMC article.
28 results