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α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson's disease.
Cole TA, Zhao H, Collier TJ, Sandoval I, Sortwell CE, Steece-Collier K, Daley BF, Booms A, Lipton J, Welch M, Berman M, Jandreski L, Graham D, Weihofen A, Celano S, Schulz E, Cole-Strauss A, Luna E, Quach D, Mohan A, Bennett CF, Swayze EE, Kordasiewicz HB, Luk KC, Paumier KL. Cole TA, et al. Among authors: lipton j. JCI Insight. 2021 Mar 8;6(5):e135633. doi: 10.1172/jci.insight.135633. JCI Insight. 2021. PMID: 33682798 Free PMC article.
Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.
Paumier KL, Luk KC, Manfredsson FP, Kanaan NM, Lipton JW, Collier TJ, Steece-Collier K, Kemp CJ, Celano S, Schulz E, Sandoval IM, Fleming S, Dirr E, Polinski NK, Trojanowski JQ, Lee VM, Sortwell CE. Paumier KL, et al. Among authors: lipton jw. Neurobiol Dis. 2015 Oct;82:185-199. doi: 10.1016/j.nbd.2015.06.003. Epub 2015 Jun 17. Neurobiol Dis. 2015. PMID: 26093169 Free PMC article.
Subthalamic Nucleus Deep Brain Stimulation Does Not Modify the Functional Deficits or Axonopathy Induced by Nigrostriatal α-Synuclein Overexpression.
Fischer DL, Manfredsson FP, Kemp CJ, Cole-Strauss A, Lipton JW, Duffy MF, Polinski NK, Steece-Collier K, Collier TJ, Gombash SE, Buhlinger DJ, Sortwell CE. Fischer DL, et al. Among authors: lipton jw. Sci Rep. 2017 Nov 27;7(1):16356. doi: 10.1038/s41598-017-16690-x. Sci Rep. 2017. PMID: 29180681 Free PMC article.
Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits.
Gezer AO, Kochmanski J, VanOeveren SE, Cole-Strauss A, Kemp CJ, Patterson JR, Miller KM, Kuhn NC, Herman DE, McIntire A, Lipton JW, Luk KC, Fleming SM, Sortwell CE, Bernstein AI. Gezer AO, et al. Among authors: lipton jw. Neurobiol Dis. 2020 Jul;141:104947. doi: 10.1016/j.nbd.2020.104947. Epub 2020 May 15. Neurobiol Dis. 2020. PMID: 32422283 Free PMC article.
1,073 results