Scuron MD - Search Results

1

Ruxolitinib Cream Has Dual Efficacy on Pruritus and Inflammation in Experimental Dermatitis.

Scuron MD, Fay BL, Connell AJ, Peel MT, Smith PA. Scuron MD, et al. Front Immunol. 2021 Feb 15;11:620098. doi: 10.3389/fimmu.2020.620098. eCollection 2020. Front Immunol. 2021. PMID: 33658996 Free PMC article.

2

Preclinical characterization of itacitinib (INCB039110), a novel selective inhibitor of JAK1, for the treatment of inflammatory diseases.

Covington M, He X, Scuron M, Li J, Collins R, Juvekar A, Shin N, Favata M, Gallagher K, Sarah S, Xue CB, Peel M, Burke K, Oliver J, Fay B, Yao W, Huang T, Scherle P, Diamond S, Newton R, Zhang Y, Smith P. Covington M, et al. Eur J Pharmacol. 2020 Oct 15;885:173505. doi: 10.1016/j.ejphar.2020.173505. Epub 2020 Aug 28. Eur J Pharmacol. 2020. PMID: 32861662

3

Spontaneous Model of Sjögren's Syndrome in NOD Mice.

Scuron MD, Fay B, Oliver J, Smith P. Scuron MD, et al. Curr Protoc Pharmacol. 2019 Sep;86(1):e65. doi: 10.1002/cpph.65. Curr Protoc Pharmacol. 2019. PMID: 31539922

4

The PI3Kδ inhibitor parsaclisib ameliorates pathology and reduces autoantibody formation in preclinical models of systemic lupus erythematosus and Sjӧgren's syndrome.

Scuron MD, Fay BL, Connell AJ, Oliver J, Smith PA. Scuron MD, et al. Int Immunopharmacol. 2021 Sep;98:107904. doi: 10.1016/j.intimp.2021.107904. Epub 2021 Jun 29. Int Immunopharmacol. 2021. PMID: 34214886 Free article.

5

The Cytolethal Distending Toxin Contributes to Microbial Virulence and Disease Pathogenesis by Acting As a Tri-Perditious Toxin.

Scuron MD, Boesze-Battaglia K, Dlakić M, Shenker BJ. Scuron MD, et al. Front Cell Infect Microbiol. 2016 Dec 5;6:168. doi: 10.3389/fcimb.2016.00168. eCollection 2016. Front Cell Infect Microbiol. 2016. PMID: 27995094 Free PMC article. Review.

6

The toxicity of the Aggregatibacter actinomycetemcomitans cytolethal distending toxin correlates with its phosphatidylinositol-3,4,5-triphosphate phosphatase activity.

Shenker BJ, Boesze-Battaglia K, Scuron MD, Walker LP, Zekavat A, Dlakić M. Shenker BJ, et al. Among authors: scuron md. Cell Microbiol. 2016 Feb;18(2):223-43. doi: 10.1111/cmi.12497. Epub 2015 Sep 2. Cell Microbiol. 2016. PMID: 26247396

7

The Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Active Subunit CdtB Contains a Cholesterol Recognition Sequence Required for Toxin Binding and Subunit Internalization.

Boesze-Battaglia K, Walker LP, Zekavat A, Dlakić M, Scuron MD, Nygren P, Shenker BJ. Boesze-Battaglia K, et al. Among authors: scuron md. Infect Immun. 2015 Oct;83(10):4042-55. doi: 10.1128/IAI.00788-15. Epub 2015 Jul 27. Infect Immun. 2015. PMID: 26216427 Free PMC article.

8

Aggregatibacter actinomycetemcomitans cytolethal distending toxin activates the NLRP3 inflammasome in human macrophages, leading to the release of proinflammatory cytokines.

Shenker BJ, Ojcius DM, Walker LP, Zekavat A, Scuron MD, Boesze-Battaglia K. Shenker BJ, et al. Among authors: scuron md. Infect Immun. 2015 Apr;83(4):1487-96. doi: 10.1128/IAI.03132-14. Epub 2015 Feb 2. Infect Immun. 2015. PMID: 25644004 Free PMC article.

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