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Kynurenine Relaxes Arteries of Normotensive Women and Those With Preeclampsia.
Worton SA, Pritchard HAT, Greenwood SL, Alakrawi M, Heazell AEP, Wareing M, Greenstein A, Myers JE. Worton SA, et al. Among authors: alakrawi m. Circ Res. 2021 May 28;128(11):1679-1693. doi: 10.1161/CIRCRESAHA.120.317612. Epub 2021 Mar 3. Circ Res. 2021. PMID: 33656370 Free PMC article.
Functionally linked potassium channel activity in cerebral endothelial and smooth muscle cells is compromised in Alzheimer's disease.
Taylor JL, Pritchard HAT, Walsh KR, Strangward P, White C, Hill-Eubanks D, Alakrawi M, Hennig GW, Allan SM, Nelson MT, Greenstein AS. Taylor JL, et al. Among authors: alakrawi m. Proc Natl Acad Sci U S A. 2022 Jun 28;119(26):e2204581119. doi: 10.1073/pnas.2204581119. Epub 2022 Jun 21. Proc Natl Acad Sci U S A. 2022. PMID: 35727988 Free PMC article.
Sustained Benefit of Zanubrutinib vs Ibrutinib in Patients With R/R CLL/SLL: Final Comparative Analysis of ALPINE.
Brown JR, Eichhorst B, Lamanna N, O'Brien SM MD, Tam CS, Qiu L, Jurczak W, Zhou K, Šimkovič M, Mayer J, Gillespie-Twardy A, Ferrajoli A, Ganly PS, Weinkove R, Grosicki S, Mital A, Robak T Prof, Osterborg A, Yimer HA, Wang MY, Salmi T, Wang L, Li J, Wu K, Cohen AC, Shadman M. Brown JR, et al. Blood. 2024 Sep 24:blood.2024024667. doi: 10.1182/blood.2024024667. Online ahead of print. Blood. 2024. PMID: 39316666
Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM).
Engers JL, Baker LA, Chang S, Luscombe VB, Rodriguez AL, Niswender CM, Cho HP, Bubser M, Gray AT, Jones CK, Peng W, Rook JM, Bridges TM, Boutaud O, Conn PJ, Engers DW, Lindsley CW, Temple KJ. Engers JL, et al. ACS Chem Neurosci. 2024 Sep 24. doi: 10.1021/acschemneuro.4c00465. Online ahead of print. ACS Chem Neurosci. 2024. PMID: 39316465
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