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A versatile platform for locus-scale genome rewriting and verification.
Brosh R, Laurent JM, Ordoñez R, Huang E, Hogan MS, Hitchcock AM, Mitchell LA, Pinglay S, Cadley JA, Luther RD, Truong DM, Boeke JD, Maurano MT. Brosh R, et al. Among authors: boeke jd. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2023952118. doi: 10.1073/pnas.2023952118. Proc Natl Acad Sci U S A. 2021. PMID: 33649239 Free PMC article.
SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes.
Shen Y, Stracquadanio G, Wang Y, Yang K, Mitchell LA, Xue Y, Cai Y, Chen T, Dymond JS, Kang K, Gong J, Zeng X, Zhang Y, Li Y, Feng Q, Xu X, Wang J, Wang J, Yang H, Boeke JD, Bader JS. Shen Y, et al. Among authors: boeke jd. Genome Res. 2016 Jan;26(1):36-49. doi: 10.1101/gr.193433.115. Epub 2015 Nov 13. Genome Res. 2016. PMID: 26566658 Free PMC article.
GENOME ENGINEERING. The Genome Project-Write.
Boeke JD, Church G, Hessel A, Kelley NJ, Arkin A, Cai Y, Carlson R, Chakravarti A, Cornish VW, Holt L, Isaacs FJ, Kuiken T, Lajoie M, Lessor T, Lunshof J, Maurano MT, Mitchell LA, Rine J, Rosser S, Sanjana NE, Silver PA, Valle D, Wang H, Way JC, Yang L. Boeke JD, et al. Science. 2016 Jul 8;353(6295):126-7. doi: 10.1126/science.aaf6850. Epub 2016 Jun 2. Science. 2016. PMID: 27256881 No abstract available.
424 results