Walker VM - Search Results

1

Mendelian randomization for studying the effects of perturbing drug targets.

Gill D, Georgakis MK, Walker VM, Schmidt AF, Gkatzionis A, Freitag DF, Finan C, Hingorani AD, Howson JMM, Burgess S, Swerdlow DI, Davey Smith G, Holmes MV, Dichgans M, Scott RA, Zheng J, Psaty BM, Davies NM. Gill D, et al. Among authors: walker vm. Wellcome Open Res. 2021 Feb 10;6:16. doi: 10.12688/wellcomeopenres.16544.2. eCollection 2021. Wellcome Open Res. 2021. PMID: 33644404 Free PMC article. Review.

2

Can commonly prescribed drugs be repurposed for the prevention or treatment of Alzheimer's and other neurodegenerative diseases? Protocol for an observational cohort study in the UK Clinical Practice Research Datalink.

Walker VM, Davies NM, Jones T, Kehoe PG, Martin RM. Walker VM, et al. BMJ Open. 2016 Dec 13;6(12):e012044. doi: 10.1136/bmjopen-2016-012044. BMJ Open. 2016. PMID: 27965247 Free PMC article.

3

Power calculator for instrumental variable analysis in pharmacoepidemiology.

Walker VM, Davies NM, Windmeijer F, Burgess S, Martin RM. Walker VM, et al. Int J Epidemiol. 2017 Oct 1;46(5):1627-1632. doi: 10.1093/ije/dyx090. Int J Epidemiol. 2017. PMID: 28575313 Free PMC article.

4

Mendelian randomization: a novel approach for the prediction of adverse drug events and drug repurposing opportunities.

Walker VM, Davey Smith G, Davies NM, Martin RM. Walker VM, et al. Int J Epidemiol. 2017 Dec 1;46(6):2078-2089. doi: 10.1093/ije/dyx207. Int J Epidemiol. 2017. PMID: 29040597 Free PMC article.

5

What is the impact of regulatory guidance and expiry of drug patents on dementia drug prescriptions in England? A trend analysis in the Clinical Practice Research Datalink.

Walker VM, Davies NM, Kehoe PG, Martin RM. Walker VM, et al. Alzheimers Res Ther. 2018 May 29;10(1):51. doi: 10.1186/s13195-018-0379-6. Alzheimers Res Ther. 2018. PMID: 29843807 Free PMC article.

6

Repurposing antihypertensive drugs for the prevention of Alzheimer's disease: a Mendelian randomization study.

Walker VM, Kehoe PG, Martin RM, Davies NM. Walker VM, et al. Int J Epidemiol. 2020 Aug 1;49(4):1132-1140. doi: 10.1093/ije/dyz155. Int J Epidemiol. 2020. PMID: 31335937 Free PMC article.

7

Using the MR-Base platform to investigate risk factors and drug targets for thousands of phenotypes.

Walker VM, Davies NM, Hemani G, Zheng J, Haycock PC, Gaunt TR, Davey Smith G, Martin RM. Walker VM, et al. Wellcome Open Res. 2019 Nov 7;4:113. doi: 10.12688/wellcomeopenres.15334.2. eCollection 2019. Wellcome Open Res. 2019. PMID: 31448343 Free PMC article.

8

Comparison with randomized controlled trials as a strategy for evaluating instruments in Mendelian randomization.

Gill D, Walker VM, Martin RM, Davies NM, Tzoulaki I. Gill D, et al. Among authors: walker vm. Int J Epidemiol. 2020 Aug 1;49(4):1404-1406. doi: 10.1093/ije/dyz236. Int J Epidemiol. 2020. PMID: 31764983 No abstract available.

9

Mendelian randomization applied to pharmaceutical use: the case of metformin and lung cancer.

Yarmolinsky J, Bull CJ, Walker VM, Nounu A, Davey Smith G. Yarmolinsky J, et al. Among authors: walker vm. Int J Epidemiol. 2020 Aug 1;49(4):1410-1411. doi: 10.1093/ije/dyaa059. Int J Epidemiol. 2020. PMID: 32356895 Free PMC article. No abstract available.

10

Comparison of Antihypertensive Drug Classes for Dementia Prevention.

Walker VM, Davies NM, Martin RM, Kehoe PG. Walker VM, et al. Epidemiology. 2020 Nov;31(6):852-859. doi: 10.1097/EDE.0000000000001245. Epidemiology. 2020. PMID: 32841987 Free PMC article.

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