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Loss of Optineurin Drives Cancer Immune Evasion via Palmitoylation-Dependent IFNGR1 Lysosomal Sorting and Degradation.
Du W, Hua F, Li X, Zhang J, Li S, Wang W, Zhou J, Wang W, Liao P, Yan Y, Li G, Wei S, Grove S, Vatan L, Zgodziński W, Majewski M, Wallner G, Chen H, Kryczek I, Fang JY, Zou W. Du W, et al. Among authors: grove s. Cancer Discov. 2021 Jul;11(7):1826-1843. doi: 10.1158/2159-8290.CD-20-1571. Epub 2021 Feb 24. Cancer Discov. 2021. PMID: 33627378 Free PMC article.
Cancer SLC43A2 alters T cell methionine metabolism and histone methylation.
Bian Y, Li W, Kremer DM, Sajjakulnukit P, Li S, Crespo J, Nwosu ZC, Zhang L, Czerwonka A, Pawłowska A, Xia H, Li J, Liao P, Yu J, Vatan L, Szeliga W, Wei S, Grove S, Liu JR, McLean K, Cieslik M, Chinnaiyan AM, Zgodziński W, Wallner G, Wertel I, Okła K, Kryczek I, Lyssiotis CA, Zou W. Bian Y, et al. Among authors: grove s. Nature. 2020 Sep;585(7824):277-282. doi: 10.1038/s41586-020-2682-1. Epub 2020 Sep 2. Nature. 2020. PMID: 32879489 Free PMC article.
Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance.
Lin H, Kryczek I, Li S, Green MD, Ali A, Hamasha R, Wei S, Vatan L, Szeliga W, Grove S, Li X, Li J, Wang W, Yan Y, Choi JE, Li G, Bian Y, Xu Y, Zhou J, Yu J, Xia H, Wang W, Alva A, Chinnaiyan AM, Cieslik M, Zou W. Lin H, et al. Among authors: grove s. Cancer Cell. 2021 Apr 12;39(4):480-493.e6. doi: 10.1016/j.ccell.2020.12.023. Epub 2021 Jan 28. Cancer Cell. 2021. PMID: 33513345 Free PMC article.
LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy.
Li G, Kryczek I, Nam J, Li X, Li S, Li J, Wei S, Grove S, Vatan L, Zhou J, Du W, Lin H, Wang T, Subramanian C, Moon JJ, Cieslik M, Cohen M, Zou W. Li G, et al. Among authors: grove s. Nat Cell Biol. 2021 May;23(5):526-537. doi: 10.1038/s41556-021-00672-3. Epub 2021 May 6. Nat Cell Biol. 2021. PMID: 33958760 Free PMC article.
CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4.
Liao P, Wang W, Wang W, Kryczek I, Li X, Bian Y, Sell A, Wei S, Grove S, Johnson JK, Kennedy PD, Gijón M, Shah YM, Zou W. Liao P, et al. Among authors: grove s. Cancer Cell. 2022 Apr 11;40(4):365-378.e6. doi: 10.1016/j.ccell.2022.02.003. Epub 2022 Feb 24. Cancer Cell. 2022. PMID: 35216678 Free PMC article.
Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy.
Li G, Choi JE, Kryczek I, Sun Y, Liao P, Li S, Wei S, Grove S, Vatan L, Nelson R, Schaefer G, Allen SG, Sankar K, Fecher LA, Mendiratta-Lala M, Frankel TL, Qin A, Waninger JJ, Tezel A, Alva A, Lao CD, Ramnath N, Cieslik M, Harms PW, Green MD, Chinnaiyan AM, Zou W. Li G, et al. Among authors: grove s. Cancer Cell. 2023 Feb 13;41(2):304-322.e7. doi: 10.1016/j.ccell.2022.12.008. Epub 2023 Jan 12. Cancer Cell. 2023. PMID: 36638784 Free PMC article.
Targeting the lipid kinase PIKfyve upregulates surface expression of MHC class I to augment cancer immunotherapy.
Bao Y, Qiao Y, Choi JE, Zhang Y, Mannan R, Cheng C, He T, Zheng Y, Yu J, Gondal M, Cruz G, Grove S, Cao X, Su F, Wang R, Chang Y, Kryczek I, Cieslik M, Green MD, Zou W, Chinnaiyan AM. Bao Y, et al. Among authors: grove s. Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2314416120. doi: 10.1073/pnas.2314416120. Epub 2023 Nov 27. Proc Natl Acad Sci U S A. 2023. PMID: 38011559 Free PMC article.
136 results