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Deletion of Myeloid Interferon Regulatory Factor 4 (Irf4) in Mouse Model Protects against Kidney Fibrosis after Ischemic Injury by Decreased Macrophage Recruitment and Activation.
Sasaki K, Terker AS, Pan Y, Li Z, Cao S, Wang Y, Niu A, Wang S, Fan X, Zhang MZ, Harris RC. Sasaki K, et al. Among authors: wang y, wang s. J Am Soc Nephrol. 2021 May 3;32(5):1037-1052. doi: 10.1681/ASN.2020071010. Epub 2021 Feb 22. J Am Soc Nephrol. 2021. PMID: 33619052 Free PMC article.
Selective activation of epidermal growth factor receptor in renal proximal tubule induces tubulointerstitial fibrosis.
Overstreet JM, Wang Y, Wang X, Niu A, Gewin LS, Yao B, Harris RC, Zhang MZ. Overstreet JM, et al. Among authors: wang x, wang y. FASEB J. 2017 Oct;31(10):4407-4421. doi: 10.1096/fj.201601359RR. Epub 2017 Jun 16. FASEB J. 2017. PMID: 28626027 Free PMC article.
This study provides definitive evidence that sustained activation of EGFR in proximal epithelia is sufficient to cause spontaneous, progressive renal tubulointerstitial fibrosis, evident by epithelial dedifferentiation, increased myofibroblasts, immune cell infiltration, and incr …
This study provides definitive evidence that sustained activation of EGFR in proximal epithelia is sufficient to cause spontaneous, progress …
ErbB4 deletion predisposes to development of metabolic syndrome in mice.
Zeng F, Wang Y, Kloepfer LA, Wang S, Harris RC. Zeng F, et al. Among authors: wang y, wang s. Am J Physiol Endocrinol Metab. 2018 Oct 1;315(4):E583-E593. doi: 10.1152/ajpendo.00166.2018. Epub 2018 Jun 26. Am J Physiol Endocrinol Metab. 2018. PMID: 29944391 Free PMC article.
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