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Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates.
S Arunachalam P, Walls AC, Golden N, Atyeo C, Fischinger S, Li C, Aye P, Navarro MJ, Lai L, Edara VV, Roltgen K, Rogers K, Shirreff L, Ferrell DE, Wrenn S, Pettie D, Kraft JC, Miranda MC, Kepl E, Sydeman C, Brunette N, Murphy M, Fiala B, Carter L, White AG, Trisal M, Hsieh CL, Russell-Lodrigue K, Monjure C, Dufour J, Doyle-Meyer L, Bohm RB, Maness NJ, Roy C, Plante JA, Plante KS, Zhu A, Gorman MJ, Shin S, Shen X, Fontenot J, Gupta S, O Hagan DT, Most RV, Rappuoli R, Coffman RL, Novack D, McLellan JS, Subramaniam S, Montefiori D, Boyd SD, Flynn JL, Alter G, Villinger F, Kleanthous H, Rappaport J, Suthar M, King NP, Veesler D, Pulendran B. S Arunachalam P, et al. Among authors: suthar m. bioRxiv [Preprint]. 2021 Feb 11:2021.02.10.430696. doi: 10.1101/2021.02.10.430696. bioRxiv. 2021. Update in: Nature. 2021 Jun;594(7862):253-258. doi: 10.1038/s41586-021-03530-2. PMID: 33594366 Free PMC article. Updated. Preprint.
Systems analysis of West Nile virus infection.
Suthar MS, Pulendran B. Suthar MS, et al. Curr Opin Virol. 2014 Jun;6:70-5. doi: 10.1016/j.coviro.2014.04.010. Epub 2014 May 20. Curr Opin Virol. 2014. PMID: 24851811 Free PMC article. Review.
Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis.
Johnson BA, Xie X, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Swetnam D, Plante JA, Aguilar P, Plante KS, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Shi PY, Freiberg AN, Menachery VD. Johnson BA, et al. Among authors: suthar ms. bioRxiv [Preprint]. 2020 Aug 26:2020.08.26.268854. doi: 10.1101/2020.08.26.268854. bioRxiv. 2020. Update in: Nature. 2021 Mar;591(7849):293-299. doi: 10.1038/s41586-021-03237-4. PMID: 32869021 Free PMC article. Updated. Preprint.
Infection and mRNA-1273 vaccine antibodies neutralize SARS-CoV-2 UK variant.
Edara VV, Floyd K, Lai L, Gardner M, Hudson W, Piantadosi A, Waggoner JJ, Babiker A, Ahmed R, Xie X, Lokugamage K, Menachery V, Shi PY, Suthar MS. Edara VV, et al. Among authors: suthar ms. medRxiv [Preprint]. 2021 Feb 5:2021.02.02.21250799. doi: 10.1101/2021.02.02.21250799. medRxiv. 2021. PMID: 33564782 Free PMC article. Preprint.
A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs.
Routhu NK, Cheedarla N, Gangadhara S, Bollimpelli VS, Boddapati AK, Shiferaw A, Rahman SA, Sahoo A, Edara VV, Lai L, Floyd K, Wang S, Fischinger S, Atyeo C, Shin SA, Gumber S, Kirejczyk S, Cohen J, Jean SM, Wood JS, Connor-Stroud F, Stammen RL, Upadhyay AA, Pellegrini K, Montefiori D, Shi PY, Menachery VD, Alter G, Vanderford TH, Bosinger SE, Suthar MS, Amara RR. Routhu NK, et al. Among authors: suthar ms. Immunity. 2021 Mar 9;54(3):542-556.e9. doi: 10.1016/j.immuni.2021.02.001. Epub 2021 Feb 4. Immunity. 2021. PMID: 33631118 Free PMC article.
Reduced binding and neutralization of infection- and vaccine-induced antibodies to the B.1.351 (South African) SARS-CoV-2 variant.
Edara VV, Norwood C, Floyd K, Lai L, Davis-Gardner ME, Hudson WH, Mantus G, Nyhoff LE, Adelman MW, Fineman R, Patel S, Byram R, Gomes DN, Michael G, Abdullahi H, Beydoun N, Panganiban B, McNair N, Hellmeister K, Pitts J, Winters J, Kleinhenz J, Usher J, O'Keefe JB, Piantadosi A, Waggoner JJ, Babiker A, Stephens DS, Anderson EJ, Edupuganti S, Rouphael N, Ahmed R, Wrammert J, Suthar MS. Edara VV, et al. bioRxiv [Preprint]. 2021 Feb 22:2021.02.20.432046. doi: 10.1101/2021.02.20.432046. bioRxiv. 2021. Update in: Cell Host Microbe. 2021 Apr 14;29(4):516-521.e3. doi: 10.1016/j.chom.2021.03.009. PMID: 33655254 Free PMC article. Updated. Preprint.
Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates.
Francica JR, Flynn BJ, Foulds KE, Noe AT, Werner AP, Moore IN, Gagne M, Johnston TS, Tucker C, Davis RL, Flach B, O'Connell S, Andrew SF, Lamb E, Flebbe DR, Nurmukhambetova ST, Donaldson MM, Todd JM, Zhu AL, Atyeo C, Fischinger S, Gorman MJ, Shin S, Edara VV, Floyd K, Lai L, Tylor A, McCarthy E, Lecouturier V, Ruiz S, Berry C, Tibbitts T, Andersen H, Cook A, Dodson A, Pessaint L, Ry AV, Koutsoukos M, Gutzeit C, Teng IT, Zhou T, Li D, Haynes BF, Kwong PD, McDermott A, Lewis MG, Fu TM, Chicz R, van der Most R, Corbett KS, Suthar MS, Alter G, Roederer M, Sullivan NJ, Douek DC, Graham BS, Casimiro D, Seder RA. Francica JR, et al. Among authors: suthar ms. bioRxiv [Preprint]. 2021 Mar 2:2021.03.02.433390. doi: 10.1101/2021.03.02.433390. bioRxiv. 2021. PMID: 33688652 Free PMC article. Preprint.
291 results