Trimble CL - Search Results

1

TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers.

Nagarsheth NB, Norberg SM, Sinkoe AL, Adhikary S, Meyer TJ, Lack JB, Warner AC, Schweitzer C, Doran SL, Korrapati S, Stevanović S, Trimble CL, Kanakry JA, Bagheri MH, Ferraro E, Astrow SH, Bot A, Faquin WC, Stroncek D, Gkitsas N, Highfill S, Hinrichs CS. Nagarsheth NB, et al. Among authors: trimble cl. Nat Med. 2021 Mar;27(3):419-425. doi: 10.1038/s41591-020-01225-1. Epub 2021 Feb 8. Nat Med. 2021. PMID: 33558725 Free PMC article.

2

Characterization of HLA-A2-restricted HPV-16 E7-specific CD8(+) T-cell immune responses induced by DNA vaccines in HLA-A2 transgenic mice.

Peng S, Trimble C, He L, Tsai YC, Lin CT, Boyd DA, Pardoll D, Hung CF, Wu TC. Peng S, et al. Gene Ther. 2006 Jan;13(1):67-77. doi: 10.1038/sj.gt.3302607. Gene Ther. 2006. PMID: 16107858 Free PMC article.

3

A combination of DNA vaccines targeting human papillomavirus type 16 E6 and E7 generates potent antitumor effects.

Peng S, Tomson TT, Trimble C, He L, Hung CF, Wu TC. Peng S, et al. Gene Ther. 2006 Feb;13(3):257-65. doi: 10.1038/sj.gt.3302646. Gene Ther. 2006. PMID: 16177818 Free PMC article.

4

HLA-DQB1*02-restricted HPV-16 E7 peptide-specific CD4+ T-cell immune responses correlate with regression of HPV-16-associated high-grade squamous intraepithelial lesions.

Peng S, Trimble C, Wu L, Pardoll D, Roden R, Hung CF, Wu TC. Peng S, et al. Clin Cancer Res. 2007 Apr 15;13(8):2479-87. doi: 10.1158/1078-0432.CCR-06-2916. Clin Cancer Res. 2007. PMID: 17438108 Free PMC article.

5

Combination of treatment with death receptor 5-specific antibody with therapeutic HPV DNA vaccination generates enhanced therapeutic anti-tumor effects.

Tseng CW, Monie A, Trimble C, Alvarez RD, Huh WK, Buchsbaum DJ, Straughn JM Jr, Wang MC, Yagita H, Hung CF, Wu TC. Tseng CW, et al. Vaccine. 2008 Aug 12;26(34):4314-9. doi: 10.1016/j.vaccine.2008.06.049. Epub 2008 Jul 1. Vaccine. 2008. PMID: 18598733 Free PMC article.

6

Naturally occurring systemic immune responses to HPV antigens do not predict regression of CIN2/3.

Trimble CL, Peng S, Thoburn C, Kos F, Wu TC. Trimble CL, et al. Cancer Immunol Immunother. 2010 May;59(5):799-803. doi: 10.1007/s00262-009-0806-4. Epub 2009 Dec 13. Cancer Immunol Immunother. 2010. PMID: 20012604 Free PMC article.

7

HPV Infection-Associated Cancers: Next-Generation Technology for Diagnosis and Treatment.

Trimble CL. Trimble CL. Cancer Immunol Res. 2014 Oct;2(10):937-42. doi: 10.1158/2326-6066.CIR-14-0152. Cancer Immunol Res. 2014. PMID: 25281321 Free PMC article. Review.

8

Engineered T cells targeting E7 mediate regression of human papillomavirus cancers in a murine model.

Jin BY, Campbell TE, Draper LM, Stevanović S, Weissbrich B, Yu Z, Restifo NP, Rosenberg SA, Trimble CL, Hinrichs CS. Jin BY, et al. Among authors: trimble cl. JCI Insight. 2018 Apr 19;3(8):e99488. doi: 10.1172/jci.insight.99488. eCollection 2018 Apr 19. JCI Insight. 2018. PMID: 29669936 Free PMC article. Clinical Trial.

9

Towards identifying new therapeutic targets in cancers attributable to HPV.

Trimble CL. Trimble CL. Gynecol Oncol. 2018 May;149(2):225-226. doi: 10.1016/j.ygyno.2018.03.061. Gynecol Oncol. 2018. PMID: 29685611 No abstract available.

10

Current status of therapeutic HPV vaccines.

Clark KT, Trimble CL. Clark KT, et al. Among authors: trimble cl. Gynecol Oncol. 2020 Feb;156(2):503-510. doi: 10.1016/j.ygyno.2019.12.017. Epub 2019 Dec 20. Gynecol Oncol. 2020. PMID: 31870557 Review.

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