MacFarlane M - Search Results

1

Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate.

Fox JL, Hughes MA, Meng X, Sarnowska NA, Powley IR, Jukes-Jones R, Dinsdale D, Ragan TJ, Fairall L, Schwabe JWR, Morone N, Cain K, MacFarlane M. Fox JL, et al. Among authors: macfarlane m. Nat Commun. 2021 Feb 5;12(1):819. doi: 10.1038/s41467-020-20806-9. Nat Commun. 2021. PMID: 33547302 Free PMC article.

2

Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes.

Cohen GM, Sun XM, Fearnhead H, MacFarlane M, Brown DG, Snowden RT, Dinsdale D. Cohen GM, et al. Among authors: macfarlane m. J Immunol. 1994 Jul 15;153(2):507-16. J Immunol. 1994. PMID: 8021492

3

DNA degradation and proteolysis in thymocyte apoptosis.

Fearnhead HO, MacFarlane M, Dinsdale D, Cohen GM. Fearnhead HO, et al. Among authors: macfarlane m. Toxicol Lett. 1995 Dec;82-83:135-41. doi: 10.1016/0378-4274(95)03473-0. Toxicol Lett. 1995. PMID: 8597041

4

Processing/activation of at least four interleukin-1beta converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells.

MacFarlane M, Cain K, Sun XM, Alnemri ES, Cohen GM. MacFarlane M, et al. J Cell Biol. 1997 Apr 21;137(2):469-79. doi: 10.1083/jcb.137.2.469. J Cell Biol. 1997. PMID: 9128256 Free PMC article.

5

Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis.

MacFarlane M, Merrison W, Dinsdale D, Cohen GM. MacFarlane M, et al. J Cell Biol. 2000 Mar 20;148(6):1239-54. doi: 10.1083/jcb.148.6.1239. J Cell Biol. 2000. PMID: 10725337 Free PMC article.

6

Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis.

Bratton SB, MacFarlane M, Cain K, Cohen GM. Bratton SB, et al. Among authors: macfarlane m. Exp Cell Res. 2000 Apr 10;256(1):27-33. doi: 10.1006/excr.2000.4835. Exp Cell Res. 2000. PMID: 10739648 Review.

7

Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia.

MacFarlane M, Harper N, Snowden RT, Dyer MJ, Barnett GA, Pringle JH, Cohen GM. MacFarlane M, et al. Oncogene. 2002 Oct 3;21(44):6809-18. doi: 10.1038/sj.onc.1205853. Oncogene. 2002. PMID: 12360407

8

Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis.

Harper N, Hughes M, MacFarlane M, Cohen GM. Harper N, et al. Among authors: macfarlane m. J Biol Chem. 2003 Jul 11;278(28):25534-41. doi: 10.1074/jbc.M303399200. Epub 2003 Apr 29. J Biol Chem. 2003. PMID: 12721308 Free article.

9

Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling.

Harper N, Hughes MA, Farrow SN, Cohen GM, MacFarlane M. Harper N, et al. Among authors: macfarlane m. J Biol Chem. 2003 Nov 7;278(45):44338-47. doi: 10.1074/jbc.M307376200. Epub 2003 Aug 14. J Biol Chem. 2003. PMID: 12920112 Free article.

10

Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex.

Twiddy D, Brown DG, Adrain C, Jukes R, Martin SJ, Cohen GM, MacFarlane M, Cain K. Twiddy D, et al. Among authors: macfarlane m. J Biol Chem. 2004 May 7;279(19):19665-82. doi: 10.1074/jbc.M311388200. Epub 2004 Mar 1. J Biol Chem. 2004. PMID: 14993223 Free article.

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