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The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support.
Irmisch A, Bonilla X, Chevrier S, Lehmann KV, Singer F, Toussaint NC, Esposito C, Mena J, Milani ES, Casanova R, Stekhoven DJ, Wegmann R, Jacob F, Sobottka B, Goetze S, Kuipers J, Sarabia Del Castillo J, Prummer M, Tuncel MA, Menzel U, Jacobs A, Engler S, Sivapatham S, Frei AL, Gut G, Ficek J, Miglino N; Tumor Profiler Consortium; Aebersold R, Bacac M, Beerenwinkel N, Beisel C, Bodenmiller B, Dummer R, Heinzelmann-Schwarz V, Koelzer VH, Manz MG, Moch H, Pelkmans L, Snijder B, Theocharides APA, Tolnay M, Wicki A, Wollscheid B, Rätsch G, Levesque MP. Irmisch A, et al. Among authors: wegmann r. Cancer Cell. 2021 Mar 8;39(3):288-293. doi: 10.1016/j.ccell.2021.01.004. Epub 2021 Jan 21. Cancer Cell. 2021. PMID: 33482122 Free article.
SCIM: universal single-cell matching with unpaired feature sets.
Stark SG, Ficek J, Locatello F, Bonilla X, Chevrier S, Singer F; Tumor Profiler Consortium; Rätsch G, Lehmann KV. Stark SG, et al. Bioinformatics. 2020 Dec 30;36(Suppl_2):i919-i927. doi: 10.1093/bioinformatics/btaa843. Bioinformatics. 2020. PMID: 33381818 Free PMC article.
ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma.
Eichhoff OM, Stoffel CI, Käsler J, Briker L, Turko P, Karsai G, Zila N, Paulitschke V, Cheng PF, Leitner A, Bileck A, Zamboni N, Irmisch A, Balazs Z, Tastanova A, Pascoal S, Johansen P, Wegmann R, Mena J, Othman A, Viswanathan VS, Wenzina J, Aloia A, Saltari A, Dzung A; TuPro Consortium; Krauthammer M, Schreiber SL, Hornemann T, Distel M, Snijder B, Dummer R, Levesque MP. Eichhoff OM, et al. Among authors: wegmann r. Cancer Res. 2023 Apr 4;83(7):1128-1146. doi: 10.1158/0008-5472.CAN-22-1826. Cancer Res. 2023. PMID: 36946761
scROSHI: robust supervised hierarchical identification of single cells.
Prummer M, Bertolini A, Bosshard L, Barkmann F, Yates J, Boeva V; Tumor Profiler Consortium; Stekhoven D, Singer F. Prummer M, et al. NAR Genom Bioinform. 2023 Jun 16;5(2):lqad058. doi: 10.1093/nargab/lqad058. eCollection 2023 Jun. NAR Genom Bioinform. 2023. PMID: 37332656 Free PMC article.
Probabilistic pathway-based multimodal factor analysis.
Immer A, Stark SG, Jacob F, Bonilla X, Thomas T, Kahles A, Goetze S, Milani ES, Wollscheid B; Tumor Profiler Consortium; Rätsch G, Lehmann KV. Immer A, et al. Bioinformatics. 2024 Jun 28;40(Suppl 1):i189-i198. doi: 10.1093/bioinformatics/btae216. Bioinformatics. 2024. PMID: 38940152 Free PMC article.
High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity.
Lee S, Weiss T, Bühler M, Mena J, Lottenbach Z, Wegmann R, Sun M, Bihl M, Augustynek B, Baumann SP, Goetze S, van Drogen A, Pedrioli PGA, Penton D, Festl Y, Buck A, Kirschenbaum D, Zeitlberger AM, Neidert MC, Vasella F, Rushing EJ, Wollscheid B, Hediger MA, Weller M, Snijder B. Lee S, et al. Among authors: wegmann r. Nat Med. 2024 Nov;30(11):3196-3208. doi: 10.1038/s41591-024-03224-y. Epub 2024 Sep 20. Nat Med. 2024. PMID: 39304781 Free PMC article.
192 results