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Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors.
MAbs. 2021 Jan-Dec;13(1):1850395. doi: 10.1080/19420862.2020.1850395.
MAbs. 2021.
PMID: 33459147
Free PMC article.
Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer.
Root AR, Cao W, Li B, LaPan P, Meade C, Sanford J, Jin M, O'Sullivan C, Cummins E, Lambert M, Sheehan AD, Ma W, Gatto S, Kerns K, Lam K, D'Antona AM, Zhu L, Brady WA, Benard S, King A, He T, Racie L, Arai M, Barrett D, Stochaj W, LaVallie ER, Apgar JR, Svenson K, Mosyak L, Yang Y, Chichili GR, Liu L, Li H, Burke S, Johnson S, Alderson R, Finlay WJJ, Lin L, Olland S, Somers W, Bonvini E, Gerber HP, May C, Moore PA, Tchistiakova L, Bloom L.
Root AR, et al. Among authors: sheehan ad.
Antibodies (Basel). 2016 Mar 4;5(1):6. doi: 10.3390/antib5010006.
Antibodies (Basel). 2016.
PMID: 31557987
Free PMC article.
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Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding function.
Su Z, Brooks J, Pelker J, Andreyeva T, Sobon H, Gifford R, Powers M, Wang J, Dower C, Hegen M, Messing D, Sheehan AD, Brennan JJ.
Su Z, et al. Among authors: sheehan ad.
PLoS One. 2023 Jan 20;18(1):e0280590. doi: 10.1371/journal.pone.0280590. eCollection 2023.
PLoS One. 2023.
PMID: 36662882
Free PMC article.
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