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Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors.
Zhang G, Baidin V, Pahil KS, Moison E, Tomasek D, Ramadoss NS, Chatterjee AK, McNamara CW, Young TS, Schultz PG, Meredith TC, Kahne D. Zhang G, et al. Among authors: baidin v. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6834-6839. doi: 10.1073/pnas.1804670115. Epub 2018 May 7. Proc Natl Acad Sci U S A. 2018. PMID: 29735709 Free PMC article.
Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery.
Buss JA, Baidin V, Welsh MA, Flores-Kim J, Cho H, Wood BM, Uehara T, Walker S, Kahne D, Bernhardt TG. Buss JA, et al. Among authors: baidin v. Antimicrob Agents Chemother. 2018 Dec 21;63(1):e01530-18. doi: 10.1128/AAC.01530-18. Print 2019 Jan. Antimicrob Agents Chemother. 2018. PMID: 30323039 Free PMC article.
Rapid Inhibitor Discovery by Exploiting Synthetic Lethality.
Muscato JD, Morris HG, Mychack A, Rajagopal M, Baidin V, Hesser AR, Lee W, İnecik K, Wilson LJ, Kraml CM, Meredith TC, Walker S. Muscato JD, et al. Among authors: baidin v. J Am Chem Soc. 2022 Mar 2;144(8):3696-3705. doi: 10.1021/jacs.1c12697. Epub 2022 Feb 16. J Am Chem Soc. 2022. PMID: 35170959 Free PMC article.
Author Correction: A novel antibiotic class targeting the lipopolysaccharide transporter.
Zampaloni C, Mattei P, Bleicher K, Winther L, Thäte C, Bucher C, Adam JM, Alanine A, Amrein KE, Baidin V, Bieniossek C, Bissantz C, Boess F, Cantrill C, Clairfeuille T, Dey F, Di Giorgio P, du Castel P, Dylus D, Dzygiel P, Felici A, García-Alcalde F, Haldimann A, Leipner M, Leyn S, Louvel S, Misson P, Osterman A, Pahil K, Rigo S, Schäublin A, Scharf S, Schmitz P, Stoll T, Trauner A, Zoffmann S, Kahne D, Young JAT, Lobritz MA, Bradley KA. Zampaloni C, et al. Among authors: baidin v. Nature. 2024 Jul;631(8022):E17. doi: 10.1038/s41586-024-07641-4. Nature. 2024. PMID: 38992182 Free PMC article. No abstract available.
A new antibiotic traps lipopolysaccharide in its intermembrane transporter.
Pahil KS, Gilman MSA, Baidin V, Clairfeuille T, Mattei P, Bieniossek C, Dey F, Muri D, Baettig R, Lobritz M, Bradley K, Kruse AC, Kahne D. Pahil KS, et al. Among authors: baidin v. Nature. 2024 Jan;625(7995):572-577. doi: 10.1038/s41586-023-06799-7. Epub 2024 Jan 3. Nature. 2024. PMID: 38172635 Free PMC article.
13 results