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Fine-Needle Aspiration-Based Patient-Derived Cancer Organoids.
Vilgelm AE, Bergdorf K, Wolf M, Bharti V, Shattuck-Brandt R, Blevins A, Jones C, Phifer C, Lee M, Lowe C, Hongo R, Boyd K, Netterville J, Rohde S, Idrees K, Bauer JA, Westover D, Reinfeld B, Baregamian N, Richmond A, Rathmell WK, Lee E, McDonald OG, Weiss VL. Vilgelm AE, et al. Among authors: lee e, lee m. iScience. 2020 Aug 21;23(8):101408. doi: 10.1016/j.isci.2020.101408. Epub 2020 Jul 24. iScience. 2020. PMID: 32771978 Free PMC article.
Obtaining patient-derived cancer organoid cultures via fine-needle aspiration.
Phifer CJ, Bergdorf KN, Bechard ME, Vilgelm A, Baregamian N, McDonald OG, Lee E, Weiss VL. Phifer CJ, et al. Among authors: lee e. STAR Protoc. 2020 Dec 21;2(1):100220. doi: 10.1016/j.xpro.2020.100220. eCollection 2021 Mar 19. STAR Protoc. 2020. PMID: 33377121 Free PMC article.
USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling.
Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, Robbins DJ, Thorne CA, Ahmed Y, Lee E. Kassel S, et al. Among authors: lee e. Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7. Sci Signal. 2023. PMID: 36749823 Free PMC article.
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling.
Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E. Ng VH, et al. Among authors: lee e. Nat Commun. 2023 Oct 5;14(1):6173. doi: 10.1038/s41467-023-41836-z. Nat Commun. 2023. PMID: 37798301 Free PMC article.
Wnt/β-catenin signaling is a therapeutic target in anaplastic thyroid carcinoma.
Diaz D, Bergdorf K, Loberg MA, Phifer CJ, Xu GJ, Sheng Q, Chen SC, Byrant JM, Tigue ML, Hartmann H, Rohde SL, Netterville JL, Baregamian N, Goettel JA, Ye F, Lee E, Weiss VL. Diaz D, et al. Among authors: lee e. Endocrine. 2024 Oct;86(1):114-118. doi: 10.1007/s12020-024-03887-0. Epub 2024 May 28. Endocrine. 2024. PMID: 38806891 Free PMC article.
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