Mani C - Search Results

1

Improved Antitumor Activity of the Fluoropyrimidine Polymer CF10 in Preclinical Colorectal Cancer Models through Distinct Mechanistic and Pharmacologic Properties.

Gmeiner WH, Dominijanni A, Haber AO, Ghiraldeli LP, Caudell DL, D'Agostino R Jr, Pasche BC, Smith TL, Deng Z, Kiren S, Mani C, Palle K, Brody JR. Gmeiner WH, et al. Among authors: mani c. Mol Cancer Ther. 2021 Mar;20(3):553-563. doi: 10.1158/1535-7163.MCT-20-0516. Epub 2020 Dec 23. Mol Cancer Ther. 2021. PMID: 33361273 Free PMC article.

2

Aberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and Chemoresistance.

Palle K, Mani C, Tripathi K, Athar M. Palle K, et al. Among authors: mani c. Cancers (Basel). 2015 Nov 27;7(4):2330-51. doi: 10.3390/cancers7040894. Cancers (Basel). 2015. PMID: 26633513 Free PMC article. Review.

3

Rad18 is required for functional interactions between FANCD2, BRCA2, and Rad51 to repair DNA topoisomerase 1-poisons induced lesions and promote fork recovery.

Tripathi K, Mani C, Clark DW, Palle K. Tripathi K, et al. Among authors: mani c. Oncotarget. 2016 Mar 15;7(11):12537-53. doi: 10.18632/oncotarget.7247. Oncotarget. 2016. PMID: 26871286 Free PMC article.

4

Detection and evaluation of estrogen DNA-adducts and their carcinogenic effects in cultured human cells using biotinylated estradiol.

Tripathi K, Mani C, Somasagara RR, Clark DW, Ananthapur V, Vinaya K, Palle K. Tripathi K, et al. Among authors: mani c. Mol Carcinog. 2017 Mar;56(3):1010-1020. doi: 10.1002/mc.22566. Epub 2016 Sep 21. Mol Carcinog. 2017. PMID: 27597267

5

RAD6 promotes chemoresistance in ovarian cancer.

Clark DW, Mani C, Palle K. Clark DW, et al. Among authors: mani c. Mol Cell Oncol. 2017 Dec 18;5(1):e1392403. doi: 10.1080/23723556.2017.1392403. eCollection 2018. Mol Cell Oncol. 2017. PMID: 29404391 Free PMC article.

6

Thymineless Death by the Fluoropyrimidine Polymer F10 Involves Replication Fork Collapse and Is Enhanced by Chk1 Inhibition.

Mani C, Pai S, Papke CM, Palle K, Gmeiner WH. Mani C, et al. Neoplasia. 2018 Dec;20(12):1236-1245. doi: 10.1016/j.neo.2018.10.006. Epub 2018 Nov 12. Neoplasia. 2018. PMID: 30439567 Free PMC article.

7

DNA repair fidelity in stem cell maintenance, health, and disease.

Mani C, Reddy PH, Palle K. Mani C, et al. Biochim Biophys Acta Mol Basis Dis. 2020 Apr 1;1866(4):165444. doi: 10.1016/j.bbadis.2019.03.017. Epub 2019 Apr 4. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 30953688 Free PMC article. Review.

8

Prexasertib treatment induces homologous recombination deficiency and synergizes with olaparib in triple-negative breast cancer cells.

Mani C, Jonnalagadda S, Lingareddy J, Awasthi S, Gmeiner WH, Palle K. Mani C, et al. Breast Cancer Res. 2019 Sep 6;21(1):104. doi: 10.1186/s13058-019-1192-2. Breast Cancer Res. 2019. PMID: 31492187 Free PMC article.

9

The multifunctional protein PACS-1 is required for HDAC2- and HDAC3-dependent chromatin maturation and genomic stability.

Mani C, Tripathi K, Luan S, Clark DW, Andrews JF, Vindigni A, Thomas G, Palle K. Mani C, et al. Oncogene. 2020 Mar;39(12):2583-2596. doi: 10.1038/s41388-020-1167-x. Epub 2020 Jan 27. Oncogene. 2020. PMID: 31988453 Free PMC article.

10

AraC-FdUMP[10] Is a Next-Generation Fluoropyrimidine with Potent Antitumor Activity in PDAC and Synergy with PARG Inhibition.

Haber AO, Jain A, Mani C, Nevler A, Agostini LC, Golan T, Palle K, Yeo CJ, Gmeiner WH, Brody JR. Haber AO, et al. Among authors: mani c. Mol Cancer Res. 2021 Apr;19(4):565-572. doi: 10.1158/1541-7786.MCR-20-0985. Epub 2021 Feb 16. Mol Cancer Res. 2021. PMID: 33593942 Free PMC article.

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