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Page 1
Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit.
Kraushar ML, Krupp F, Harnett D, Turko P, Ambrozkiewicz MC, Sprink T, Imami K, Günnigmann M, Zinnall U, Vieira-Vieira CH, Schaub T, Münster-Wandowski A, Bürger J, Borisova E, Yamamoto H, Rasin MR, Ohler U, Beule D, Mielke T, Tarabykin V, Landthaler M, Kramer G, Vida I, Selbach M, Spahn CMT. Kraushar ML, et al. Mol Cell. 2021 Jan 21;81(2):304-322.e16. doi: 10.1016/j.molcel.2020.11.037. Epub 2020 Dec 22. Mol Cell. 2021. PMID: 33357414 Free PMC article.
Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development.
Popovitchenko T, Park Y, Page NF, Luo X, Krsnik Z, Liu Y, Salamon I, Stephenson JD, Kraushar ML, Volk NL, Patel SM, Wijeratne HRS, Li D, Suthar KS, Wach A, Sun M, Arnold SJ, Akamatsu W, Okano H, Paillard L, Zhang H, Buyske S, Kostovic I, De Rubeis S, Hart RP, Rasin MR. Popovitchenko T, et al. Among authors: kraushar ml. Nat Commun. 2020 Apr 3;11(1):1674. doi: 10.1038/s41467-020-15412-8. Nat Commun. 2020. PMID: 32245946 Free PMC article.
Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates.
Hochmair J, Exner C, Franck M, Dominguez-Baquero A, Diez L, Brognaro H, Kraushar ML, Mielke T, Radbruch H, Kaniyappan S, Falke S, Mandelkow E, Betzel C, Wegmann S. Hochmair J, et al. Among authors: kraushar ml. EMBO J. 2022 Jun 1;41(11):e108882. doi: 10.15252/embj.2021108882. Epub 2022 Mar 17. EMBO J. 2022. PMID: 35298090 Free PMC article.
A critical period of translational control during brain development at codon resolution.
Harnett D, Ambrozkiewicz MC, Zinnall U, Rusanova A, Borisova E, Drescher AN, Couce-Iglesias M, Villamil G, Dannenberg R, Imami K, Münster-Wandowski A, Fauler B, Mielke T, Selbach M, Landthaler M, Spahn CMT, Tarabykin V, Ohler U, Kraushar ML. Harnett D, et al. Among authors: kraushar ml. Nat Struct Mol Biol. 2022 Dec;29(12):1277-1290. doi: 10.1038/s41594-022-00882-9. Epub 2022 Dec 8. Nat Struct Mol Biol. 2022. PMID: 36482253 Free PMC article.
Protein translation rate determines neocortical neuron fate.
Borisova E, Newman AG, Couce Iglesias M, Dannenberg R, Schaub T, Qin B, Rusanova A, Brockmann M, Koch J, Daniels M, Turko P, Jahn O, Kaplan DR, Rosário M, Iwawaki T, Spahn CMT, Rosenmund C, Meierhofer D, Kraushar ML, Tarabykin V, Ambrozkiewicz MC. Borisova E, et al. Among authors: kraushar ml. Nat Commun. 2024 Jun 7;15(1):4879. doi: 10.1038/s41467-024-49198-w. Nat Commun. 2024. PMID: 38849354 Free PMC article.
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