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Discovery of CA-4948, an Orally Bioavailable IRAK4 Inhibitor for Treatment of Hematologic Malignancies.
Gummadi VR, Boruah A, Ainan BR, Vare BR, Manda S, Gondle HP, Kumar SN, Mukherjee S, Gore ST, Krishnamurthy NR, Marappan S, Nayak SS, Nellore K, Balasubramanian WR, Bhumireddy A, Giri S, Gopinath S, Samiulla DS, Daginakatte G, Basavaraju A, Chelur S, Eswarappa R, Belliappa C, Subramanya HS, Booher RN, Ramachandra M, Samajdar S. Gummadi VR, et al. Among authors: balasubramanian wr. ACS Med Chem Lett. 2020 Oct 14;11(12):2374-2381. doi: 10.1021/acsmedchemlett.0c00255. eCollection 2020 Dec 10. ACS Med Chem Lett. 2020. PMID: 33335659 Free PMC article.
Design, synthesis, and biological evaluation of phenyl thiazole-based AR-V7 degraders.
Bhumireddy A, Bandaru NVMR, Raghurami Reddy B, Gore ST, Mukherjee S, Balasubramanian WR, Sumanth Kumar V, Alapati KS, Venkata Gowri Chandra Sekhar K, Nellore K, Abbineni C, Samajdar S. Bhumireddy A, et al. Among authors: balasubramanian wr. Bioorg Med Chem Lett. 2022 Jan 1;55:128448. doi: 10.1016/j.bmcl.2021.128448. Epub 2021 Nov 9. Bioorg Med Chem Lett. 2022. PMID: 34767914