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Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning.
Unger EK, Keller JP, Altermatt M, Liang R, Matsui A, Dong C, Hon OJ, Yao Z, Sun J, Banala S, Flanigan ME, Jaffe DA, Hartanto S, Carlen J, Mizuno GO, Borden PM, Shivange AV, Cameron LP, Sinning S, Underhill SM, Olson DE, Amara SG, Temple Lang D, Rudnick G, Marvin JS, Lavis LD, Lester HA, Alvarez VA, Fisher AJ, Prescher JA, Kash TL, Yarov-Yarovoy V, Gradinaru V, Looger LL, Tian L. Unger EK, et al. Among authors: kash tl. Cell. 2020 Dec 23;183(7):1986-2002.e26. doi: 10.1016/j.cell.2020.11.040. Epub 2020 Dec 16. Cell. 2020. PMID: 33333022 Free PMC article.
New insights on neurobiological mechanisms underlying alcohol addiction.
Cui C, Noronha A, Morikawa H, Alvarez VA, Stuber GD, Szumlinski KK, Kash TL, Roberto M, Wilcox MV. Cui C, et al. Among authors: kash tl. Neuropharmacology. 2013 Apr;67:223-32. doi: 10.1016/j.neuropharm.2012.09.022. Epub 2012 Nov 13. Neuropharmacology. 2013. PMID: 23159531 Free PMC article. Review.
Sex-Dependent Modulation of Anxiety and Fear by 5-HT1A Receptors in the Bed Nucleus of the Stria Terminalis.
Marcinkiewcz CA, Bierlein-De La Rosa G, Dorrier CE, McKnight M, DiBerto JF, Pati D, Gianessi CA, Hon OJ, Tipton G, McElligott ZA, Delpire E, Kash TL. Marcinkiewcz CA, et al. Among authors: kash tl. ACS Chem Neurosci. 2019 Jul 17;10(7):3154-3166. doi: 10.1021/acschemneuro.8b00594. Epub 2019 Jun 17. ACS Chem Neurosci. 2019. PMID: 31140276 Free PMC article.
Bed Nucleus of the Stria Terminalis (BNST) neurons containing the serotonin 5HT2c receptor modulate operant alcohol self-administration behavior in mice.
Flanigan ME, Gianessi C, Castle M, Dorlean W, Sides T, Kash TL. Flanigan ME, et al. Among authors: kash tl. bioRxiv [Preprint]. 2023 Sep 27:2023.09.26.559653. doi: 10.1101/2023.09.26.559653. bioRxiv. 2023. Update in: Neuropsychopharmacology. 2024 Mar;49(4):709-719. doi: 10.1038/s41386-023-01753-7. PMID: 37808816 Free PMC article. Updated. Preprint.
120 results