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Dual Pharmacological Targeting of HDACs and PDE5 Inhibits Liver Disease Progression in a Mouse Model of Biliary Inflammation and Fibrosis.
Claveria-Cabello A, Colyn L, Uriarte I, Latasa MU, Arechederra M, Herranz JM, Alvarez L, Urman JM, Martinez-Chantar ML, Banales JM, Sangro B, Rombouts K, Oyarzabal J, Marin JJG, Berasain C, Avila MA, Fernandez-Barrena MG. Claveria-Cabello A, et al. Among authors: alvarez l. Cancers (Basel). 2020 Dec 13;12(12):3748. doi: 10.3390/cancers12123748. Cancers (Basel). 2020. PMID: 33322158 Free PMC article.
Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma.
Bárcena-Varela M, Caruso S, Llerena S, Álvarez-Sola G, Uriarte I, Latasa MU, Urtasun R, Rebouissou S, Alvarez L, Jimenez M, Santamaría E, Rodriguez-Ortigosa C, Mazza G, Rombouts K, San José-Eneriz E, Rabal O, Agirre X, Iraburu M, Santos-Laso A, Banales JM, Zucman-Rossi J, Prósper F, Oyarzabal J, Berasain C, Ávila MA, Fernández-Barrena MG. Bárcena-Varela M, et al. Among authors: alvarez l, alvarez sola g. Hepatology. 2019 Feb;69(2):587-603. doi: 10.1002/hep.30168. Epub 2019 Jan 4. Hepatology. 2019. PMID: 30014490
Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis.
Barcena-Varela M, Paish H, Alvarez L, Uriarte I, Latasa MU, Santamaria E, Recalde M, Garate M, Claveria A, Colyn L, Arechederra M, Iraburu MJ, Milkiewicz M, Milkiewicz P, Sangro B, Robinson SM, French J, Pardo-Saganta A, Oyarzabal J, Prosper F, Rombouts K, Oakley F, Mann J, Berasain C, Avila MA, G Fernandez-Barrena M. Barcena-Varela M, et al. Among authors: alvarez l. Gut. 2021 Feb;70(2):388-400. doi: 10.1136/gutjnl-2019-320205. Epub 2020 Apr 23. Gut. 2021. PMID: 32327527
Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models.
Olaizola P, Lee-Law PY, Fernandez-Barrena MG, Alvarez L, Cadamuro M, Azkargorta M, O'Rourke CJ, Caballero-Camino FJ, Olaizola I, Macias RIR, Marin JJG, Serrano-Maciá M, Martinez-Chantar ML, Avila MA, Aspichueta P, Calvisi DF, Evert M, Fabris L, Castro RE, Elortza F, Andersen JB, Bujanda L, Rodrigues PM, Perugorria MJ, Banales JM. Olaizola P, et al. Among authors: alvarez l. J Hepatol. 2022 Jul;77(1):177-190. doi: 10.1016/j.jhep.2022.02.007. Epub 2022 Feb 23. J Hepatol. 2022. PMID: 35217064 Free article.
No correlation between the expression of FXR and genes involved in multidrug resistance phenotype of primary liver tumors.
Martinez-Becerra P, Vaquero J, Romero MR, Lozano E, Anadon C, Macias RI, Serrano MA, Grañé-Boladeras N, Muñoz-Bellvis L, Alvarez L, Sangro B, Pastor-Anglada M, Marin JJ. Martinez-Becerra P, et al. Among authors: alvarez l. Mol Pharm. 2012 Jun 4;9(6):1693-704. doi: 10.1021/mp300028a. Epub 2012 May 1. Mol Pharm. 2012. PMID: 22524153
Molecular characteristics of atopic dermatitis patients with clinical remission.
Sánchez A, Caraballo A, Alvarez L, Valencia O, Restrepo MN, Gaviria R, Velasquez-Lopera M, Urrego JR, Sánchez J. Sánchez A, et al. Among authors: alvarez l. World Allergy Organ J. 2024 Oct 30;17(11):100983. doi: 10.1016/j.waojou.2024.100983. eCollection 2024 Nov. World Allergy Organ J. 2024. PMID: 39534446 Free PMC article.
Impact of a multifaceted intervention programme on antibiotic prescribing and dispensing in four patient-centred settings in five European countries. The HAPPY PATIENT project.
García-Sangenís A, Lykkegaard J, Hansen MP, González López-Valcárcel B, Raynal F, Vallejo-Torres L, Bjerrum L, Chalkidou A, Jensen JN, Rebnord I, Lindberg BH, Taxis K, Lambert M, Radzeviciene R, Jaruseviciene L, Touboul Lundgren P, Bruno P, Lesage V, Kowalczyk A, Godycki-Cwirko M, Lionis C, Karkana MN, Anastasaki M, Hansen MB, Olsen JK, Søndergaard J, Modena D, Mally S, Álvarez L, Llor C. García-Sangenís A, et al. Among authors: alvarez l. Fam Pract. 2024 Nov 12:cmae064. doi: 10.1093/fampra/cmae064. Online ahead of print. Fam Pract. 2024. PMID: 39531344
A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants.
Ferreira LT, Cassiano GC, Alvarez LCS, Okombo J, Calit J, Fontinha D, Gil-Iturbe E, Coyle R, Andrade CH, Sunnerhagen P, Bargieri DY, Prudêncio M, Quick M, Cravo PV, Lee MCS, Fidock DA, Costa FTM. Ferreira LT, et al. Among authors: alvarez lcs. PLoS Pathog. 2024 Oct 29;20(10):e1012627. doi: 10.1371/journal.ppat.1012627. eCollection 2024 Oct. PLoS Pathog. 2024. PMID: 39471233 Free PMC article.
1,533 results