Hock MB - Search Results

1

Early Phase Clinical Immunogenicity of Valoctocogene Roxaparvovec, an AAV5-Mediated Gene Therapy for Hemophilia A.

Long BR, Veron P, Kuranda K, Hardet R, Mitchell N, Hayes GM, Wong WY, Lau K, Li M, Hock MB, Zoog SJ, Vettermann C, Mingozzi F, Schweighardt B. Long BR, et al. Among authors: hock mb. Mol Ther. 2021 Feb 3;29(2):597-610. doi: 10.1016/j.ymthe.2020.12.008. Epub 2020 Dec 10. Mol Ther. 2021. PMID: 33309883 Free PMC article.

2

Immunogenicity/hypersensitivity of biologics.

Leach MW, Rottman JB, Hock MB, Finco D, Rojko JL, Beyer JC. Leach MW, et al. Among authors: hock mb. Toxicol Pathol. 2014 Jan;42(1):293-300. doi: 10.1177/0192623313510987. Epub 2013 Nov 14. Toxicol Pathol. 2014. PMID: 24240973

3

A Proposal to Redefine Clinical Immunogenicity Assessment.

Mytych DT, Hock MB, Kroenke M, Jawa V, Kaliyaperumal A, Zhou Y. Mytych DT, et al. Among authors: hock mb. AAPS J. 2017 May;19(3):599-602. doi: 10.1208/s12248-017-0059-7. Epub 2017 Feb 28. AAPS J. 2017. PMID: 28247192

4

Biomarkers for non-human primate type-I hypersensitivity: antigen-specific immunoglobulin E assays.

Clark D, Shiota F, Forte C, Narayanan P, Mytych DT, Hock MB. Clark D, et al. Among authors: hock mb. J Immunol Methods. 2013 Jun 28;392(1-2):29-37. doi: 10.1016/j.jim.2013.03.007. Epub 2013 Mar 27. J Immunol Methods. 2013. PMID: 23541488

5

Clinical immunogenicity of the d-amino acid peptide therapeutic etelcalcetide: Method development challenges and anti-drug antibody clinical impact assessments.

Kroenke MA, Weeraratne DK, Deng H, Sloey B, Subramanian R, Wu B, Serenko M, Hock MB. Kroenke MA, et al. Among authors: hock mb. J Immunol Methods. 2017 Jun;445:37-44. doi: 10.1016/j.jim.2017.03.005. Epub 2017 Mar 6. J Immunol Methods. 2017. PMID: 28274835 Clinical Trial.

6

Immunogenicity testing strategy and bioanalytical assays for antibody-drug conjugates.

Hoofring SA, Lopez R, Hock MB, Kaliyaperumal A, Patel SK, Swanson SJ, Chirmule N, Starcevic M. Hoofring SA, et al. Among authors: hock mb. Bioanalysis. 2013 May;5(9):1041-55. doi: 10.4155/bio.13.10. Bioanalysis. 2013. PMID: 23641695

7

T-cell-dependent antibody responses in the rat: forms and sources of keyhole limpet hemocyanin matter.

Lebrec H, Hock MB, Sundsmo JS, Mytych DT, Chow H, Carlock LL, Joubert MK, Reindel J, Zhou L, Bussiere JL. Lebrec H, et al. Among authors: hock mb. J Immunotoxicol. 2014 Jul-Sep;11(3):213-21. doi: 10.3109/1547691X.2013.822948. Epub 2013 Aug 20. J Immunotoxicol. 2014. PMID: 23961896

8

Pharmacokinetics, Biotransformation, and Excretion of [¹⁴C]Etelcalcetide (AMG 416) Following a Single Microtracer Intravenous Dose in Patients with Chronic Kidney Disease on Hemodialysis.

Subramanian R, Zhu X, Hock MB, Sloey BJ, Wu B, Wilson SF, Egbuna O, Slatter JG, Xiao J, Skiles GL. Subramanian R, et al. Among authors: hock mb. Clin Pharmacokinet. 2017 Feb;56(2):179-192. doi: 10.1007/s40262-016-0433-0. Clin Pharmacokinet. 2017. PMID: 27517676 Free PMC article. Clinical Trial.

9

Immunogenicity of antibody drug conjugates: bioanalytical methods and monitoring strategy for a novel therapeutic modality.

Hock MB, Thudium KE, Carrasco-Triguero M, Schwabe NF. Hock MB, et al. AAPS J. 2015 Jan;17(1):35-43. doi: 10.1208/s12248-014-9684-6. Epub 2014 Nov 8. AAPS J. 2015. PMID: 25380723 Free PMC article.

10

Clinical Pharmacokinetics and Pharmacodynamics of Etelcalcetide, a Novel Calcimimetic for Treatment of Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease on Hemodialysis.

Wu B, Melhem M, Subramanian R, Chen P, Jaramilla Sloey B, Fouqueray B, Hock MB, Skiles GL, Chow AT, Lee E. Wu B, et al. Among authors: hock mb. J Clin Pharmacol. 2018 Jun;58(6):717-726. doi: 10.1002/jcph.1090. Epub 2018 Mar 13. J Clin Pharmacol. 2018. PMID: 29534286 Review.

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