Siegwart DJ - Search Results

1

A Systematic Study of Unsaturation in Lipid Nanoparticles Leads to Improved mRNA Transfection In Vivo.

Lee SM, Cheng Q, Yu X, Liu S, Johnson LT, Siegwart DJ. Lee SM, et al. Among authors: siegwart dj. Angew Chem Int Ed Engl. 2021 Mar 8;60(11):5848-5853. doi: 10.1002/anie.202013927. Epub 2021 Feb 1. Angew Chem Int Ed Engl. 2021. PMID: 33305471 Free PMC article.

2

Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA.

Miller JB, Zhang S, Kos P, Xiong H, Zhou K, Perelman SS, Zhu H, Siegwart DJ. Miller JB, et al. Among authors: siegwart dj. Angew Chem Int Ed Engl. 2017 Jan 19;56(4):1059-1063. doi: 10.1002/anie.201610209. Epub 2016 Dec 16. Angew Chem Int Ed Engl. 2017. PMID: 27981708 Free PMC article.

3

Systemic mRNA Delivery to the Lungs by Functional Polyester-based Carriers.

Yan Y, Xiong H, Zhang X, Cheng Q, Siegwart DJ. Yan Y, et al. Among authors: siegwart dj. Biomacromolecules. 2017 Dec 11;18(12):4307-4315. doi: 10.1021/acs.biomac.7b01356. Epub 2017 Nov 27. Biomacromolecules. 2017. PMID: 29141136

4

Dendrimer-Based Lipid Nanoparticles Deliver Therapeutic FAH mRNA to Normalize Liver Function and Extend Survival in a Mouse Model of Hepatorenal Tyrosinemia Type I.

Cheng Q, Wei T, Jia Y, Farbiak L, Zhou K, Zhang S, Wei Y, Zhu H, Siegwart DJ. Cheng Q, et al. Among authors: siegwart dj. Adv Mater. 2018 Dec;30(52):e1805308. doi: 10.1002/adma.201805308. Epub 2018 Oct 25. Adv Mater. 2018. PMID: 30368954

5

Lipid-Modified Aminoglycosides for mRNA Delivery to the Liver.

Yu X, Liu S, Cheng Q, Wei T, Lee S, Zhang D, Siegwart DJ. Yu X, et al. Among authors: siegwart dj. Adv Healthc Mater. 2020 Apr;9(7):e1901487. doi: 10.1002/adhm.201901487. Epub 2020 Feb 28. Adv Healthc Mater. 2020. PMID: 32108440 Free PMC article.

6

Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing.

Cheng Q, Wei T, Farbiak L, Johnson LT, Dilliard SA, Siegwart DJ. Cheng Q, et al. Among authors: siegwart dj. Nat Nanotechnol. 2020 Apr;15(4):313-320. doi: 10.1038/s41565-020-0669-6. Epub 2020 Apr 6. Nat Nanotechnol. 2020. PMID: 32251383 Free PMC article.

7

Hydrophobic Domain Structure of Linear-Dendritic Poly(ethylene glycol) Lipids Affects RNA Delivery of Lipid Nanoparticles.

Zhou K, Johnson LT, Xiong H, Barrios S, Minnig JT, Yan Y, Abram B, Yu X, Siegwart DJ. Zhou K, et al. Among authors: siegwart dj. Mol Pharm. 2020 May 4;17(5):1575-1585. doi: 10.1021/acs.molpharmaceut.9b01288. Epub 2020 Apr 23. Mol Pharm. 2020. PMID: 32267707

8

Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing.

Wei T, Cheng Q, Min YL, Olson EN, Siegwart DJ. Wei T, et al. Among authors: siegwart dj. Nat Commun. 2020 Jun 26;11(1):3232. doi: 10.1038/s41467-020-17029-3. Nat Commun. 2020. PMID: 32591530 Free PMC article.

9

Theranostic dendrimer-based lipid nanoparticles containing PEGylated BODIPY dyes for tumor imaging and systemic mRNA delivery in vivo.

Xiong H, Liu S, Wei T, Cheng Q, Siegwart DJ. Xiong H, et al. Among authors: siegwart dj. J Control Release. 2020 Sep 10;325:198-205. doi: 10.1016/j.jconrel.2020.06.030. Epub 2020 Jul 3. J Control Release. 2020. PMID: 32629133 Free PMC article.

10

Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing.

Wei T, Cheng Q, Farbiak L, Anderson DG, Langer R, Siegwart DJ. Wei T, et al. Among authors: siegwart dj. ACS Nano. 2020 Aug 25;14(8):9243-9262. doi: 10.1021/acsnano.0c04707. Epub 2020 Jul 22. ACS Nano. 2020. PMID: 32697075 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

77 results

Search Page

Filters