Wulff H - Search Results

1

A non-hallucinogenic psychedelic analogue with therapeutic potential.

Cameron LP, Tombari RJ, Lu J, Pell AJ, Hurley ZQ, Ehinger Y, Vargas MV, McCarroll MN, Taylor JC, Myers-Turnbull D, Liu T, Yaghoobi B, Laskowski LJ, Anderson EI, Zhang G, Viswanathan J, Brown BM, Tjia M, Dunlap LE, Rabow ZT, Fiehn O, Wulff H, McCorvy JD, Lein PJ, Kokel D, Ron D, Peters J, Zuo Y, Olson DE. Cameron LP, et al. Among authors: wulff h. Nature. 2021 Jan;589(7842):474-479. doi: 10.1038/s41586-020-3008-z. Epub 2020 Dec 9. Nature. 2021. PMID: 33299186 Free PMC article.

2

Development of a QPatch automated electrophysiology assay for identifying KCa3.1 inhibitors and activators.

Jenkins DP, Yu W, Brown BM, Løjkner LD, Wulff H. Jenkins DP, et al. Among authors: wulff h. Assay Drug Dev Technol. 2013 Nov-Dec;11(9-10):551-60. doi: 10.1089/adt.2013.543. Assay Drug Dev Technol. 2013. PMID: 24351043 Free PMC article.

3

Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia.

Sahdeo S, Scott BD, McMackin MZ, Jasoliya M, Brown B, Wulff H, Perlman SL, Pook MA, Cortopassi GA. Sahdeo S, et al. Among authors: wulff h. Hum Mol Genet. 2014 Dec 20;23(25):6848-62. doi: 10.1093/hmg/ddu408. Epub 2014 Aug 11. Hum Mol Genet. 2014. PMID: 25113747 Free PMC article.

4

The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant.

Coleman N, Nguyen HM, Cao Z, Brown BM, Jenkins DP, Zolkowska D, Chen YJ, Tanaka BS, Goldin AL, Rogawski MA, Pessah IN, Wulff H. Coleman N, et al. Among authors: wulff h. Neurotherapeutics. 2015 Jan;12(1):234-49. doi: 10.1007/s13311-014-0305-y. Neurotherapeutics. 2015. PMID: 25256961 Free PMC article.

5

Rapid throughput analysis demonstrates that chemicals with distinct seizurogenic mechanisms differentially alter Ca2+ dynamics in networks formed by hippocampal neurons in culture.

Cao Z, Zou X, Cui Y, Hulsizer S, Lein PJ, Wulff H, Pessah IN. Cao Z, et al. Among authors: wulff h. Mol Pharmacol. 2015 Apr;87(4):595-605. doi: 10.1124/mol.114.096701. Epub 2015 Jan 12. Mol Pharmacol. 2015. PMID: 25583085 Free PMC article.

6

Chasing the Elusive Benzofuran Impurity of the THR Antagonist NH-3: Synthesis, Isotope Labeling, and Biological Activity.

Singh L, Pressly B, Mengeling BJ, Fettinger JC, Furlow JD, Lein PJ, Wulff H, Singh V. Singh L, et al. Among authors: wulff h. J Org Chem. 2016 Mar 4;81(5):1870-6. doi: 10.1021/acs.joc.5b02665. Epub 2016 Feb 18. J Org Chem. 2016. PMID: 26849160

7

Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents.

Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ. Pessah IN, et al. Among authors: wulff h. Ann N Y Acad Sci. 2016 Aug;1378(1):124-136. doi: 10.1111/nyas.13137. Epub 2016 Jul 28. Ann N Y Acad Sci. 2016. PMID: 27467073 Free PMC article. Review.

8

From the Cover: BDE-47 and BDE-49 Inhibit Axonal Growth in Primary Rat Hippocampal Neuron-Glia Co-Cultures via Ryanodine Receptor-Dependent Mechanisms.

Chen H, Streifel KM, Singh V, Yang D, Mangini L, Wulff H, Lein PJ. Chen H, et al. Among authors: wulff h. Toxicol Sci. 2017 Apr 1;156(2):375-386. doi: 10.1093/toxsci/kfw259. Toxicol Sci. 2017. PMID: 28003438 Free PMC article.

9

A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling.

Mengeling BJ, Wei Y, Dobrawa LN, Streekstra M, Louisse J, Singh V, Singh L, Lein PJ, Wulff H, Murk AJ, Furlow JD. Mengeling BJ, et al. Among authors: wulff h. Aquat Toxicol. 2017 Sep;190:1-10. doi: 10.1016/j.aquatox.2017.06.019. Epub 2017 Jun 21. Aquat Toxicol. 2017. PMID: 28662416 Free PMC article.

10

KCa3.1 Channel Modulators as Potential Therapeutic Compounds for Glioblastoma.

Brown BM, Pressley B, Wulff H. Brown BM, et al. Among authors: wulff h. Curr Neuropharmacol. 2018;16(5):618-626. doi: 10.2174/1570159X15666170630164226. Curr Neuropharmacol. 2018. PMID: 28676010 Free PMC article.

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