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A non-hallucinogenic psychedelic analogue with therapeutic potential.
Cameron LP, Tombari RJ, Lu J, Pell AJ, Hurley ZQ, Ehinger Y, Vargas MV, McCarroll MN, Taylor JC, Myers-Turnbull D, Liu T, Yaghoobi B, Laskowski LJ, Anderson EI, Zhang G, Viswanathan J, Brown BM, Tjia M, Dunlap LE, Rabow ZT, Fiehn O, Wulff H, McCorvy JD, Lein PJ, Kokel D, Ron D, Peters J, Zuo Y, Olson DE. Cameron LP, et al. Among authors: laskowski lj. Nature. 2021 Jan;589(7842):474-479. doi: 10.1038/s41586-020-3008-z. Epub 2020 Dec 9. Nature. 2021. PMID: 33299186 Free PMC article.
Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21.
Sahu BS, Rodriguez P, Nguyen ME, Han R, Cero C, Razzoli M, Piaggi P, Laskowski LJ, Pavlicev M, Muglia L, Mahata SK, O'Grady S, McCorvy JD, Baier LJ, Sham YY, Bartolomucci A. Sahu BS, et al. Among authors: laskowski lj. Cell Rep. 2019 Sep 3;28(10):2567-2580.e6. doi: 10.1016/j.celrep.2019.07.101. Cell Rep. 2019. PMID: 31484069 Free PMC article.
Investigation of the Structure-Activity Relationships of Psilocybin Analogues.
Klein AK, Chatha M, Laskowski LJ, Anderson EI, Brandt SD, Chapman SJ, McCorvy JD, Halberstadt AL. Klein AK, et al. Among authors: laskowski lj. ACS Pharmacol Transl Sci. 2020 Dec 14;4(2):533-542. doi: 10.1021/acsptsci.0c00176. eCollection 2021 Apr 9. ACS Pharmacol Transl Sci. 2020. PMID: 33860183 Free PMC article.
Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptor.
Kleist AB, Jenjak S, Sente A, Laskowski LJ, Szpakowska M, Calkins MM, Anderson EI, McNally LM, Heukers R, Bobkov V, Peterson FC, Thomas MA, Chevigné A, Smit MJ, McCorvy JD, Babu MM, Volkman BF. Kleist AB, et al. Among authors: laskowski lj. Science. 2022 Jul 8;377(6602):222-228. doi: 10.1126/science.abj4922. Epub 2022 Jul 7. Science. 2022. PMID: 35857540 Free PMC article.