Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity.
Abt ER, Rashid K, Le TM, Li S, Lee HR, Lok V, Li L, Creech AL, Labora AN, Mandl HK, Lam AK, Cho A, Rezek V, Wu N, Abril-Rodriguez G, Rosser EW, Mittelman SD, Hugo W, Mehrling T, Bantia S, Ribas A, Donahue TR, Crooks GM, Wu TT, Radu CG.
Abt ER, et al. Among authors: lam ak.
J Clin Invest. 2022 Aug 15;132(16):e160852. doi: 10.1172/JCI160852.
J Clin Invest. 2022.
PMID: 35653193
Free PMC article.