Schorpp K - Search Results

1

Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice.

Karlina R, Lutter D, Miok V, Fischer D, Altun I, Schöttl T, Schorpp K, Israel A, Cero C, Johnson JW, Kapser-Fischer I, Böttcher A, Keipert S, Feuchtinger A, Graf E, Strom T, Walch A, Lickert H, Walzthoeni T, Heinig M, Theis FJ, García-Cáceres C, Cypess AM, Ussar S. Karlina R, et al. Among authors: schorpp k. Life Sci Alliance. 2020 Nov 30;4(1):e202000924. doi: 10.26508/lsa.202000924. Print 2021 Jan. Life Sci Alliance. 2020. PMID: 33257475 Free PMC article.

2

Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation.

Jung B, Messias AC, Schorpp K, Geerlof A, Schneider G, Saur D, Hadian K, Sattler M, Wanker EE, Hasenöder S, Lickert H. Jung B, et al. Among authors: schorpp k. Sci Rep. 2016 Mar 2;6:22540. doi: 10.1038/srep22540. Sci Rep. 2016. PMID: 26931153 Free PMC article.

3

A high-content small molecule screen identifies novel inducers of definitive endoderm.

Korostylev A, Mahaddalkar PU, Keminer O, Hadian K, Schorpp K, Gribbon P, Lickert H. Korostylev A, et al. Among authors: schorpp k. Mol Metab. 2017 May 4;6(7):640-650. doi: 10.1016/j.molmet.2017.04.009. eCollection 2017 Jul. Mol Metab. 2017. PMID: 28702321 Free PMC article.

4

Mitochondrial Alkbh1 localizes to mtRNA granules and its knockdown induces the mitochondrial UPR in humans and C. elegans.

Wagner A, Hofmeister O, Rolland SG, Maiser A, Aasumets K, Schmitt S, Schorpp K, Feuchtinger A, Hadian K, Schneider S, Zischka H, Leonhardt H, Conradt B, Gerhold JM, Wolf A. Wagner A, et al. Among authors: schorpp k. J Cell Sci. 2019 Oct 1;132(19):jcs223891. doi: 10.1242/jcs.223891. J Cell Sci. 2019. PMID: 31434717

5

Post-surgical adhesions are triggered by calcium-dependent membrane bridges between mesothelial surfaces.

Fischer A, Koopmans T, Ramesh P, Christ S, Strunz M, Wannemacher J, Aichler M, Feuchtinger A, Walch A, Ansari M, Theis FJ, Schorpp K, Hadian K, Neumann PA, Schiller HB, Rinkevich Y. Fischer A, et al. Among authors: schorpp k. Nat Commun. 2020 Jun 17;11(1):3068. doi: 10.1038/s41467-020-16893-3. Nat Commun. 2020. PMID: 32555155 Free PMC article.

6

Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism.

Hartleben G, Schorpp K, Kwon Y, Betz B, Tsokanos FF, Dantes Z, Schäfer A, Rothenaigner I, Monroy Kuhn JM, Morigny P, Mehr L, Lin S, Seitz S, Tokarz J, Artati A, Adamsky J, Plettenburg O, Lutter D, Irmler M, Beckers J, Reichert M, Hadian K, Zeigerer A, Herzig S, Berriel Diaz M. Hartleben G, et al. Among authors: schorpp k. EMBO Mol Med. 2021 Apr 9;13(4):e12461. doi: 10.15252/emmm.202012461. Epub 2021 Mar 5. EMBO Mol Med. 2021. PMID: 33665961 Free PMC article.

7

Retinoic acid signaling is critical during the totipotency window in early mammalian development.

Iturbide A, Ruiz Tejada Segura ML, Noll C, Schorpp K, Rothenaigner I, Ruiz-Morales ER, Lubatti G, Agami A, Hadian K, Scialdone A, Torres-Padilla ME. Iturbide A, et al. Among authors: schorpp k. Nat Struct Mol Biol. 2021 Jun;28(6):521-532. doi: 10.1038/s41594-021-00590-w. Epub 2021 May 27. Nat Struct Mol Biol. 2021. PMID: 34045724 Free PMC article.

8

Three-dimensional microtissues essentially contribute to preclinical validations of therapeutic targets in breast cancer.

Falkenberg N, Höfig I, Rosemann M, Szumielewski J, Richter S, Schorpp K, Hadian K, Aubele M, Atkinson MJ, Anastasov N. Falkenberg N, et al. Among authors: schorpp k. Cancer Med. 2016 Apr;5(4):703-10. doi: 10.1002/cam4.630. Epub 2016 Jan 14. Cancer Med. 2016. PMID: 26763588 Free PMC article.

9

New small molecules targeting apoptosis and cell viability in osteosarcoma.

Maugg D, Rothenaigner I, Schorpp K, Potukuchi HK, Korsching E, Baumhoer D, Hadian K, Smida J, Nathrath M. Maugg D, et al. Among authors: schorpp k. PLoS One. 2015 Jun 3;10(6):e0129058. doi: 10.1371/journal.pone.0129058. eCollection 2015. PLoS One. 2015. PMID: 26039064 Free PMC article.

10

YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB.

Schimmack G, Schorpp K, Kutzner K, Gehring T, Brenke JK, Hadian K, Krappmann D. Schimmack G, et al. Among authors: schorpp k. Elife. 2017 Feb 28;6:e22416. doi: 10.7554/eLife.22416. Elife. 2017. PMID: 28244869 Free PMC article.

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