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A single-dose ChAdOx1-vectored vaccine provides complete protection against Nipah Bangladesh and Malaysia in Syrian golden hamsters.
van Doremalen N, Lambe T, Sebastian S, Bushmaker T, Fischer R, Feldmann F, Haddock E, Letko M, Avanzato VA, Rissanen I, LaCasse R, Scott D, Bowden TA, Gilbert S, Munster V. van Doremalen N, et al. Among authors: bowden ta. PLoS Negl Trop Dis. 2019 Jun 6;13(6):e0007462. doi: 10.1371/journal.pntd.0007462. eCollection 2019 Jun. PLoS Negl Trop Dis. 2019. PMID: 31170144 Free PMC article.
A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex.
Avanzato VA, Oguntuyo KY, Escalera-Zamudio M, Gutierrez B, Golden M, Kosakovsky Pond SL, Pryce R, Walter TS, Seow J, Doores KJ, Pybus OG, Munster VJ, Lee B, Bowden TA. Avanzato VA, et al. Among authors: bowden ta. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25057-25067. doi: 10.1073/pnas.1912503116. Epub 2019 Nov 25. Proc Natl Acad Sci U S A. 2019. PMID: 31767754 Free PMC article.
Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant.
Graham C, Seow J, Huettner I, Khan H, Kouphou N, Acors S, Winstone H, Pickering S, Galao RP, Dupont L, Lista MJ, Jimenez-Guardeño JM, Laing AG, Wu Y, Joseph M, Muir L, van Gils MJ, Ng WM, Duyvesteyn HME, Zhao Y, Bowden TA, Shankar-Hari M, Rosa A, Cherepanov P, McCoy LE, Hayday AC, Neil SJD, Malim MH, Doores KJ. Graham C, et al. Among authors: bowden ta. Immunity. 2021 Jun 8;54(6):1276-1289.e6. doi: 10.1016/j.immuni.2021.03.023. Epub 2021 Apr 1. Immunity. 2021. PMID: 33836142 Free PMC article.
Antibody evasion by the P.1 strain of SARS-CoV-2.
Dejnirattisai W, Zhou D, Supasa P, Liu C, Mentzer AJ, Ginn HM, Zhao Y, Duyvesteyn HME, Tuekprakhon A, Nutalai R, Wang B, López-Camacho C, Slon-Campos J, Walter TS, Skelly D, Costa Clemens SA, Naveca FG, Nascimento V, Nascimento F, Fernandes da Costa C, Resende PC, Pauvolid-Correa A, Siqueira MM, Dold C, Levin R, Dong T, Pollard AJ, Knight JC, Crook D, Lambe T, Clutterbuck E, Bibi S, Flaxman A, Bittaye M, Belij-Rammerstorfer S, Gilbert SC, Carroll MW, Klenerman P, Barnes E, Dunachie SJ, Paterson NG, Williams MA, Hall DR, Hulswit RJG, Bowden TA, Fry EE, Mongkolsapaya J, Ren J, Stuart DI, Screaton GR. Dejnirattisai W, et al. Among authors: bowden ta. Cell. 2021 May 27;184(11):2939-2954.e9. doi: 10.1016/j.cell.2021.03.055. Epub 2021 Mar 30. Cell. 2021. PMID: 33852911 Free PMC article.
Structure guided mutagenesis of Henipavirus Receptor Binding Proteins reveals molecular determinants of receptor usage and antibody binding epitopes.
Oguntuyo KY, Haas GD, Azarm KD, Stevens CS, Brambilla L, Kowdle S, Avanzato VA, Pryce R, Freiberg AN, Bowden TA, Lee B. Oguntuyo KY, et al. Among authors: bowden ta. bioRxiv [Preprint]. 2023 Nov 22:2023.11.22.568281. doi: 10.1101/2023.11.22.568281. bioRxiv. 2023. Update in: J Virol. 2024 Mar 19;98(3):e0183823. doi: 10.1128/jvi.01838-23 PMID: 38045373 Free PMC article. Updated. Preprint.
154 results