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Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates.
Fahlberg MD, Blair RV, Doyle-Meyers LA, Midkiff CC, Zenere G, Russell-Lodrigue KE, Monjure CJ, Haupt EH, Penney TP, Lehmicke G, Threeton BM, Golden N, Datta PK, Roy CJ, Bohm RP, Maness NJ, Fischer T, Rappaport J, Vaccari M. Fahlberg MD, et al. Among authors: golden n. Nat Commun. 2020 Nov 27;11(1):6078. doi: 10.1038/s41467-020-19967-4. Nat Commun. 2020. PMID: 33247138 Free PMC article.
Aerosolized gentamicin reduces the burden of tuberculosis in a murine model.
Roy CJ, Sivasubramani SK, Dutta NK, Mehra S, Golden NA, Killeen S, Talton JD, Hammoud BE, Didier PJ, Kaushal D. Roy CJ, et al. Antimicrob Agents Chemother. 2012 Feb;56(2):883-6. doi: 10.1128/AAC.05633-11. Epub 2011 Dec 5. Antimicrob Agents Chemother. 2012. PMID: 22143521 Free PMC article.
The Mycobacterium tuberculosis stress response factor SigH is required for bacterial burden as well as immunopathology in primate lungs.
Mehra S, Golden NA, Stuckey K, Didier PJ, Doyle LA, Russell-Lodrigue KE, Sugimoto C, Hasegawa A, Sivasubramani SK, Roy CJ, Alvarez X, Kuroda MJ, Blanchard JL, Lackner AA, Kaushal D. Mehra S, et al. J Infect Dis. 2012 Apr 15;205(8):1203-13. doi: 10.1093/infdis/jis102. Epub 2012 Mar 7. J Infect Dis. 2012. PMID: 22402035 Free PMC article.
The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence.
Mehra S, Foreman TW, Didier PJ, Ahsan MH, Hudock TA, Kissee R, Golden NA, Gautam US, Johnson AM, Alvarez X, Russell-Lodrigue KE, Doyle LA, Roy CJ, Niu T, Blanchard JL, Khader SA, Lackner AA, Sherman DR, Kaushal D. Mehra S, et al. Am J Respir Crit Care Med. 2015 May 15;191(10):1185-96. doi: 10.1164/rccm.201408-1502OC. Am J Respir Crit Care Med. 2015. PMID: 25730547 Free PMC article.
Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis.
Kaushal D, Foreman TW, Gautam US, Alvarez X, Adekambi T, Rangel-Moreno J, Golden NA, Johnson AM, Phillips BL, Ahsan MH, Russell-Lodrigue KE, Doyle LA, Roy CJ, Didier PJ, Blanchard JL, Rengarajan J, Lackner AA, Khader SA, Mehra S. Kaushal D, et al. Nat Commun. 2015 Oct 13;6:8533. doi: 10.1038/ncomms9533. Nat Commun. 2015. PMID: 26460802 Free PMC article.
CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection.
Foreman TW, Mehra S, LoBato DN, Malek A, Alvarez X, Golden NA, Bucşan AN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Roy CJ, Blanchard J, Kuroda MJ, Lackner AA, Chan J, Khader SA, Jacobs WR Jr, Kaushal D. Foreman TW, et al. Among authors: golden na. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5636-44. doi: 10.1073/pnas.1611987113. Epub 2016 Sep 6. Proc Natl Acad Sci U S A. 2016. PMID: 27601645 Free PMC article.
In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis.
Gautam US, Foreman TW, Bucsan AN, Veatch AV, Alvarez X, Adekambi T, Golden NA, Gentry KM, Doyle-Meyers LA, Russell-Lodrigue KE, Didier PJ, Blanchard JL, Kousoulas KG, Lackner AA, Kalman D, Rengarajan J, Khader SA, Kaushal D, Mehra S. Gautam US, et al. Among authors: golden na. Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):E62-E71. doi: 10.1073/pnas.1711373114. Epub 2017 Dec 18. Proc Natl Acad Sci U S A. 2018. PMID: 29255022 Free PMC article.
Mechanisms of reactivation of latent tuberculosis infection due to SIV coinfection.
Bucşan AN, Chatterjee A, Singh DK, Foreman TW, Lee TH, Threeton B, Kirkpatrick MG, Ahmed M, Golden N, Alvarez X, Hoxie JA, Mehra S, Rengarajan J, Khader SA, Kaushal D. Bucşan AN, et al. Among authors: golden n. J Clin Invest. 2019 Dec 2;129(12):5254-5260. doi: 10.1172/JCI125810. J Clin Invest. 2019. PMID: 31479428 Free PMC article.
Lung Expression of Human Angiotensin-Converting Enzyme 2 Sensitizes the Mouse to SARS-CoV-2 Infection.
Han K, Blair RV, Iwanaga N, Liu F, Russell-Lodrigue KE, Qin Z, Midkiff CC, Golden NA, Doyle-Meyers LA, Kabir ME, Chandler KE, Cutrera KL, Ren M, Monjure CJ, Lehmicke G, Fischer T, Beddingfield B, Wanek AG, Birnbaum A, Maness NJ, Roy CJ, Datta PK, Rappaport J, Kolls JK, Qin X. Han K, et al. Among authors: golden na. Am J Respir Cell Mol Biol. 2021 Jan;64(1):79-88. doi: 10.1165/rcmb.2020-0354OC. Am J Respir Cell Mol Biol. 2021. PMID: 32991819 Free PMC article.
244 results