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Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion.
Zang R, Case JB, Yutuc E, Ma X, Shen S, Gomez Castro MF, Liu Z, Zeng Q, Zhao H, Son J, Rothlauf PW, Kreutzberger AJB, Hou G, Zhang H, Bose S, Wang X, Vahey MD, Mani K, Griffiths WJ, Kirchhausen T, Fremont DH, Guo H, Diwan A, Wang Y, Diamond MS, Whelan SPJ, Ding S. Zang R, et al. Among authors: whelan spj. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):32105-32113. doi: 10.1073/pnas.2012197117. Epub 2020 Nov 25. Proc Natl Acad Sci U S A. 2020. PMID: 33239446 Free PMC article.
A broad-spectrum antiviral targeting entry of enveloped viruses.
Wolf MC, Freiberg AN, Zhang T, Akyol-Ataman Z, Grock A, Hong PW, Li J, Watson NF, Fang AQ, Aguilar HC, Porotto M, Honko AN, Damoiseaux R, Miller JP, Woodson SE, Chantasirivisal S, Fontanes V, Negrete OA, Krogstad P, Dasgupta A, Moscona A, Hensley LE, Whelan SP, Faull KF, Holbrook MR, Jung ME, Lee B. Wolf MC, et al. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62. doi: 10.1073/pnas.0909587107. Epub 2010 Jan 28. Proc Natl Acad Sci U S A. 2010. PMID: 20133606 Free PMC article.
Assembly of a functional Machupo virus polymerase complex.
Kranzusch PJ, Schenk AD, Rahmeh AA, Radoshitzky SR, Bavari S, Walz T, Whelan SP. Kranzusch PJ, et al. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20069-74. doi: 10.1073/pnas.1007152107. Epub 2010 Oct 26. Proc Natl Acad Sci U S A. 2010. PMID: 20978208 Free PMC article.
Molecular architecture of the vesicular stomatitis virus RNA polymerase.
Rahmeh AA, Schenk AD, Danek EI, Kranzusch PJ, Liang B, Walz T, Whelan SP. Rahmeh AA, et al. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20075-80. doi: 10.1073/pnas.1013559107. Epub 2010 Nov 1. Proc Natl Acad Sci U S A. 2010. PMID: 21041632 Free PMC article.
183 results