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Page 1
AAV Vectored Immunoprophylaxis for Filovirus Infections.
Rghei AD, van Lieshout LP, Santry LA, Guilleman MM, Thomas SP, Susta L, Karimi K, Bridle BW, Wootton SK. Rghei AD, et al. Among authors: thomas sp. Trop Med Infect Dis. 2020 Nov 9;5(4):169. doi: 10.3390/tropicalmed5040169. Trop Med Infect Dis. 2020. PMID: 33182447 Free PMC article. Review.
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency.
Kang MH, van Lieshout LP, Xu L, Domm JM, Vadivel A, Renesme L, Mühlfeld C, Hurskainen M, Mižíková I, Pei Y, van Vloten JP, Thomas SP, Milazzo C, Cyr-Depauw C, Whitsett JA, Nogee LM, Wootton SK, Thébaud B. Kang MH, et al. Among authors: thomas sp. Nat Commun. 2020 Aug 6;11(1):3929. doi: 10.1038/s41467-020-17577-8. Nat Commun. 2020. PMID: 32764559 Free PMC article.
A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens.
Gary EN, Warner BM, Parzych EM, Griffin BD, Zhu X, Tailor N, Tursi NJ, Chan M, Purwar M, Vendramelli R, Choi J, Frost KL, Reeder S, Liaw K, Tello E, Ali AR, Yun K, Pei Y, Thomas SP, Rghei AD, Guilleman MM, Muthumani K, Smith T, Wootton SK, Patel A, Weiner DB, Kobasa D. Gary EN, et al. Among authors: thomas sp. iScience. 2021 Jul 23;24(7):102699. doi: 10.1016/j.isci.2021.102699. Epub 2021 Jun 8. iScience. 2021. PMID: 34124612 Free PMC article.
Safety and Tolerability of the Adeno-Associated Virus Vector, AAV6.2FF, Expressing a Monoclonal Antibody in Murine and Ovine Animal Models.
Rghei AD, van Lieshout LP, McLeod BM, Pei Y, Lopes JA, Zielinska N, Baracuhy EM, Stevens BAY, Thomas SP, Yates JGE, Warner BM, Kobasa D, Fausther-Bovendo H, Kobinger GP, Karimi K, Thompson B, Bridle BW, Susta L, Wootton SK. Rghei AD, et al. Among authors: thomas sp. Biomedicines. 2021 Sep 9;9(9):1186. doi: 10.3390/biomedicines9091186. Biomedicines. 2021. PMID: 34572372 Free PMC article.
AAV-Vectored Expression of the Vascular Normalizing Agents 3TSR and Fc3TSR, and the Anti-Angiogenic Bevacizumab Extends Survival in a Murine Model of End-Stage Epithelial Ovarian Carcinoma.
Stegelmeier AA, Santry LA, Guilleman MM, Matuszewska K, Minott JA, Yates JGE, Stevens BAY, Thomas SP, Vanderkamp S, Hanada K, Pei Y, Rghei AD, van Vloten JP, Pereira M, Thompson B, Major PP, Petrik JJ, Bridle BW, Wootton SK. Stegelmeier AA, et al. Among authors: thomas sp. Biomedicines. 2022 Feb 2;10(2):362. doi: 10.3390/biomedicines10020362. Biomedicines. 2022. PMID: 35203573 Free PMC article.
AAV-monoclonal antibody expression protects mice from Ebola virus without impeding the endogenous antibody response to heterologous challenge.
van Lieshout LP, Rghei AD, Cao W, He S, Soule G, Zhu W, Thomas SP, Sorensen D, Frost K, Tierney K, Thompson B, Booth S, Safronetz D, Kulkarni RR, Bridle BW, Qiu X, Banadyga L, Wootton SK. van Lieshout LP, et al. Among authors: thomas sp. Mol Ther Methods Clin Dev. 2022 Aug 12;26:505-518. doi: 10.1016/j.omtm.2022.08.003. eCollection 2022 Sep 8. Mol Ther Methods Clin Dev. 2022. PMID: 36092367 Free PMC article.
Generation and Characterization of a SARS-CoV-2-Susceptible Mouse Model Using Adeno-Associated Virus (AAV6.2FF)-Mediated Respiratory Delivery of the Human ACE2 Gene.
Tailor N, Warner BM, Griffin BD, Tierney K, Moffat E, Frost K, Vendramelli R, Leung A, Willman M, Thomas SP, Pei Y, Booth SA, Embury-Hyatt C, Wootton SK, Kobasa D. Tailor N, et al. Among authors: thomas sp. Viruses. 2022 Dec 28;15(1):85. doi: 10.3390/v15010085. Viruses. 2022. PMID: 36680125 Free PMC article.
A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency.
Thomas SP, Domm JM, van Vloten JP, Xu L, Vadivel A, Yates JGE, Pei Y, Ingrao J, van Lieshout LP, Jackson SR, Minott JA, Achuthan A, Mehrani Y, McAusland TM, Zhang W, Karimi K, Vaughan AE, de Jong J, Kang MH, Thebaud B, Wootton SK. Thomas SP, et al. Mol Ther. 2023 Dec 6;31(12):3457-3477. doi: 10.1016/j.ymthe.2023.10.002. Epub 2023 Oct 7. Mol Ther. 2023. PMID: 37805711 Free article.
596 results