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The mode of action of sugammadex on coagulation.
Kruithof AC, Kluft C, de Kam PJ, Laterveer RH, Moerland M, Burggraaf J. Kruithof AC, et al. Among authors: de kam pj. Int J Clin Pharmacol Ther. 2021 Feb;59(2):89-98. doi: 10.5414/CP203858. Int J Clin Pharmacol Ther. 2021. PMID: 33155541
Lack of a clinically relevant effect of sugammadex on anti-Xa activity or activated partial thromboplastin time following pretreatment with either unfractionated or low-molecular-weight heparin in healthy subjects.
De Kam PJ, Kruithof AC, van Lierop MJ, Moerland M, Dennie J, Troyer MD, Langdon RB, Gutstein DE, Burggraaf J, El Galta R. De Kam PJ, et al. Int J Clin Pharmacol Ther. 2014 Aug;52(8):631-41. doi: 10.5414/CP202091. Int J Clin Pharmacol Ther. 2014. PMID: 24800921 Clinical Trial.
Interactions of sugammadex with various anticoagulants
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Kruithof AC, Kluft C, de Kam PJ, Laterveer GH, Moerland M, Burggraaf J. Kruithof AC, et al. Among authors: de kam pj. Int J Clin Pharmacol Ther. 2020 Jul;58(7):395-403. doi: 10.5414/CP203733. Int J Clin Pharmacol Ther. 2020. PMID: 32383642
A PK-PD model-based assessment of sugammadex effects on coagulation parameters.
Bosch R, van Lierop MJ, de Kam PJ, Kruithof AC, Burggraaf J, de Greef R, Visser SA, Johnson-Levonas AO, Kleijn HJ. Bosch R, et al. Among authors: de greef r, de kam pj. Eur J Pharm Sci. 2016 Mar 10;84:9-17. doi: 10.1016/j.ejps.2015.12.028. Epub 2015 Dec 30. Eur J Pharm Sci. 2016. PMID: 26747019 Clinical Trial.
Discovery and Clinical Evaluation of MK-8150, A Novel Nitric Oxide Donor With a Unique Mechanism of Nitric Oxide Release.
Knox CD, de Kam PJ, Azer K, Wong P, Ederveen AG, Shevell D, Morabito C, Meehan AG, Liu W, Reynders T, Denef JF, Mitselos A, Jonathan D, Gutstein DE, Mitra K, Sun SY, Lo MM, Cully D, Ali A. Knox CD, et al. Among authors: de kam pj. J Am Heart Assoc. 2016 Aug 25;5(9):e003493. doi: 10.1161/JAHA.116.003493. J Am Heart Assoc. 2016. PMID: 27561272 Free PMC article.
75 results