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The matrix metalloproteinase inhibitor IPR-179 has antiseizure and antiepileptogenic effects.
Broekaart DW, Bertran A, Jia S, Korotkov A, Senkov O, Bongaarts A, Mills JD, Anink JJ, Seco J, Baayen JC, Idema S, Chabrol E, Becker AJ, Wadman WJ, Tarragó T, Gorter JA, Aronica E, Prades R, Dityatev A, van Vliet EA. Broekaart DW, et al. Among authors: chabrol e. J Clin Invest. 2021 Jan 4;131(1):e138332. doi: 10.1172/JCI138332. J Clin Invest. 2021. PMID: 33141761 Free PMC article.
Neural ECM and epilepsy.
Pitkänen A, Ndode-Ekane XE, Łukasiuk K, Wilczynski GM, Dityatev A, Walker MC, Chabrol E, Dedeurwaerdere S, Vazquez N, Powell EM. Pitkänen A, et al. Among authors: chabrol e. Prog Brain Res. 2014;214:229-62. doi: 10.1016/B978-0-444-63486-3.00011-6. Prog Brain Res. 2014. PMID: 25410361 Review.
LGI1 downregulation increases neuronal circuit excitability.
Lugarà E, Kaushik R, Leite M, Chabrol E, Dityatev A, Lignani G, Walker MC. Lugarà E, et al. Among authors: chabrol e. Epilepsia. 2020 Dec;61(12):2836-2846. doi: 10.1111/epi.16736. Epub 2020 Oct 26. Epilepsia. 2020. PMID: 33104247
Epilepsy Gene Therapy Using an Engineered Potassium Channel.
Snowball A, Chabrol E, Wykes RC, Shekh-Ahmad T, Cornford JH, Lieb A, Hughes MP, Massaro G, Rahim AA, Hashemi KS, Kullmann DM, Walker MC, Schorge S. Snowball A, et al. Among authors: chabrol e. J Neurosci. 2019 Apr 17;39(16):3159-3169. doi: 10.1523/JNEUROSCI.1143-18.2019. Epub 2019 Feb 12. J Neurosci. 2019. PMID: 30755487 Free PMC article.
Glycine receptor autoantibodies disrupt inhibitory neurotransmission.
Crisp SJ, Dixon CL, Jacobson L, Chabrol E, Irani SR, Leite MI, Leschziner G, Slaght SJ, Vincent A, Kullmann DM. Crisp SJ, et al. Among authors: chabrol e. Brain. 2019 Nov 1;142(11):3398-3410. doi: 10.1093/brain/awz297. Brain. 2019. PMID: 31591639 Free PMC article.
94 results