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Ethacridine inhibits SARS-CoV-2 by inactivating viral particles in cellular models.
Li X, Lidsky P, Xiao Y, Wu CT, GarciaKnight M, Yang J, Nakayama T, Nayak JV, Jackson PK, Andino R, Shu X. Li X, et al. Among authors: andino r. bioRxiv [Preprint]. 2020 Nov 2:2020.10.28.359042. doi: 10.1101/2020.10.28.359042. bioRxiv. 2020. Update in: PLoS Pathog. 2021 Sep 3;17(9):e1009898. doi: 10.1371/journal.ppat.1009898. PMID: 33140048 Free PMC article. Updated. Preprint.
Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men.
Samuel RM, Majd H, Richter MN, Ghazizadeh Z, Zekavat SM, Navickas A, Ramirez JT, Asgharian H, Simoneau CR, Bonser LR, Koh KD, Garcia-Knight M, Tassetto M, Sunshine S, Farahvashi S, Kalantari A, Liu W, Andino R, Zhao H, Natarajan P, Erle DJ, Ott M, Goodarzi H, Fattahi F. Samuel RM, et al. Among authors: andino r. Cell Stem Cell. 2020 Dec 3;27(6):876-889.e12. doi: 10.1016/j.stem.2020.11.009. Epub 2020 Nov 17. Cell Stem Cell. 2020. PMID: 33232663 Free PMC article.
Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant.
Deng X, Garcia-Knight MA, Khalid MM, Servellita V, Wang C, Morris MK, Sotomayor-González A, Glasner DR, Reyes KR, Gliwa AS, Reddy NP, Sanchez San Martin C, Federman S, Cheng J, Balcerek J, Taylor J, Streithorst JA, Miller S, Sreekumar B, Chen PY, Schulze-Gahmen U, Taha TY, Hayashi JM, Simoneau CR, Kumar GR, McMahon S, Lidsky PV, Xiao Y, Hemarajata P, Green NM, Espinosa A, Kath C, Haw M, Bell J, Hacker JK, Hanson C, Wadford DA, Anaya C, Ferguson D, Frankino PA, Shivram H, Lareau LF, Wyman SK, Ott M, Andino R, Chiu CY. Deng X, et al. Among authors: andino r. Cell. 2021 Jun 24;184(13):3426-3437.e8. doi: 10.1016/j.cell.2021.04.025. Epub 2021 Apr 20. Cell. 2021. PMID: 33991487 Free PMC article.
In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains.
Diamond M, Chen R, Winkler E, Case J, Aziati I, Bricker T, Joshi A, Darling T, Ying B, Errico J, Shrihari S, VanBlargan L, Xie X, Gilchuk P, Zost S, Droit L, Liu Z, Stumpf S, Wang D, Handley S, Stine W, Shi PY, Garcia-Knight M, Andino R, Chiu C, Ellebedy A, Fremont D, Whelan S, Crowe J, Purcell L, Corti D, Boon A. Diamond M, et al. Among authors: andino r. Res Sq [Preprint]. 2021 Apr 23:rs.3.rs-448370. doi: 10.21203/rs.3.rs-448370/v1. Res Sq. 2021. Update in: Nature. 2021 Aug;596(7870):103-108. doi: 10.1038/s41586-021-03720-y. PMID: 34013259 Free PMC article. Updated. Preprint.
SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment.
Wu CT, Lidsky PV, Xiao Y, Lee IT, Cheng R, Nakayama T, Jiang S, Demeter J, Bevacqua RJ, Chang CA, Whitener RL, Stalder AK, Zhu B, Chen H, Goltsev Y, Tzankov A, Nayak JV, Nolan GP, Matter MS, Andino R, Jackson PK. Wu CT, et al. Among authors: andino r. Cell Metab. 2021 Aug 3;33(8):1565-1576.e5. doi: 10.1016/j.cmet.2021.05.013. Epub 2021 May 18. Cell Metab. 2021. PMID: 34081912 Free PMC article.
Ethacridine inhibits SARS-CoV-2 by inactivating viral particles.
Li X, Lidsky PV, Xiao Y, Wu CT, Garcia-Knight M, Yang J, Nakayama T, Nayak JV, Jackson PK, Andino R, Shu X. Li X, et al. Among authors: andino r. PLoS Pathog. 2021 Sep 3;17(9):e1009898. doi: 10.1371/journal.ppat.1009898. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34478458 Free PMC article.
Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers.
Nakayama T, Lee IT, Jiang S, Matter MS, Yan CH, Overdevest JB, Wu CT, Goltsev Y, Shih LC, Liao CK, Zhu B, Bai Y, Lidsky P, Xiao Y, Zarabanda D, Yang A, Easwaran M, Schürch CM, Chu P, Chen H, Stalder AK, McIlwain DR, Borchard NA, Gall PA, Dholakia SS, Le W, Xu L, Tai CJ, Yeh TH, Erickson-Direnzo E, Duran JM, Mertz KD, Hwang PH, Haslbauer JD, Jackson PK, Menter T, Andino R, Canoll PD, DeConde AS, Patel ZM, Tzankov A, Nolan GP, Nayak JV. Nakayama T, et al. Among authors: andino r. Cell Rep Med. 2021 Oct 19;2(10):100421. doi: 10.1016/j.xcrm.2021.100421. Epub 2021 Sep 28. Cell Rep Med. 2021. PMID: 34604819 Free PMC article.
A defective viral genome strategy elicits broad protective immunity against respiratory viruses.
Xiao Y, Lidsky PV, Shirogane Y, Aviner R, Wu CT, Li W, Zheng W, Talbot D, Catching A, Doitsh G, Su W, Gekko CE, Nayak A, Ernst JD, Brodsky L, Brodsky E, Rousseau E, Capponi S, Bianco S, Nakamura R, Jackson PK, Frydman J, Andino R. Xiao Y, et al. Among authors: andino r. Cell. 2021 Dec 9;184(25):6037-6051.e14. doi: 10.1016/j.cell.2021.11.023. Epub 2021 Nov 18. Cell. 2021. PMID: 34852237 Free PMC article.
204 results