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Leda-1/Pianp is targeted to the basolateral plasma membrane by a distinct intracellular juxtamembrane region and modulates barrier properties and E-Cadherin processing.
Evdokimov K, Biswas S, Schledzewski K, Winkler M, Gorzelanny C, Schneider SW, Goerdt S, Géraud C. Evdokimov K, et al. Among authors: winkler m. Biochem Biophys Res Commun. 2016 Jul 8;475(4):342-9. doi: 10.1016/j.bbrc.2016.05.092. Epub 2016 May 20. Biochem Biophys Res Commun. 2016. PMID: 27216462
Hepatic Endothelial Notch Activation Protects against Liver Metastasis by Regulating Endothelial-Tumor Cell Adhesion Independent of Angiocrine Signaling.
Wohlfeil SA, Häfele V, Dietsch B, Schledzewski K, Winkler M, Zierow J, Leibing T, Mohammadi MM, Heineke J, Sticht C, Olsavszky V, Koch PS, Géraud C, Goerdt S. Wohlfeil SA, et al. Among authors: winkler m. Cancer Res. 2019 Feb 1;79(3):598-610. doi: 10.1158/0008-5472.CAN-18-1752. Epub 2018 Dec 10. Cancer Res. 2019. PMID: 30530502
Pianp deficiency links GABAB receptor signaling and hippocampal and cerebellar neuronal cell composition to autism-like behavior.
Winkler M, Biswas S, Berger SM, Küchler M, Preisendörfer L, Choo M, Früh S, Rem PD, Enkel T, Arnold B, Komljenovic D, Sticht C, Goerdt S, Bettler B, von Bohlen Und Halbach O, Bartsch D, Géraud C. Winkler M, et al. Mol Psychiatry. 2020 Nov;25(11):2979-2993. doi: 10.1038/s41380-019-0519-9. Epub 2019 Sep 11. Mol Psychiatry. 2020. PMID: 31511635 Free PMC article.
Endothelial GATA4 controls liver fibrosis and regeneration by preventing a pathogenic switch in angiocrine signaling.
Winkler M, Staniczek T, Kürschner SW, Schmid CD, Schönhaber H, Cordero J, Kessler L, Mathes A, Sticht C, Neßling M, Uvarovskii A, Anders S, Zhang XJ, von Figura G, Hartmann D, Mogler C, Dobreva G, Schledzewski K, Géraud C, Koch PS, Goerdt S. Winkler M, et al. J Hepatol. 2021 Feb;74(2):380-393. doi: 10.1016/j.jhep.2020.08.033. Epub 2020 Sep 9. J Hepatol. 2021. PMID: 32916216 Free article.
Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation.
Koch PS, Sandorski K, Heil J, Schmid CD, Kürschner SW, Hoffmann J, Winkler M, Staniczek T, de la Torre C, Sticht C, Schledzewski K, Taketo MM, Trogisch FA, Heineke J, Géraud C, Goerdt S, Olsavszky V. Koch PS, et al. Among authors: winkler m. Front Physiol. 2021 Sep 29;12:722394. doi: 10.3389/fphys.2021.722394. eCollection 2021. Front Physiol. 2021. PMID: 34658910 Free PMC article.
1,798 results