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Page 1
Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD.
Benjamin JT, Plosa EJ, Sucre JM, van der Meer R, Dave S, Gutor S, Nichols DS, Gulleman PM, Jetter CS, Han W, Xin M, Dinella PC, Catanzarite A, Kook S, Dolma K, Lal CV, Gaggar A, Blalock JE, Newcomb DC, Richmond BW, Kropski JA, Young LR, Guttentag SH, Blackwell TS. Benjamin JT, et al. Among authors: newcomb dc. J Clin Invest. 2021 Jan 4;131(1):e139481. doi: 10.1172/JCI139481. J Clin Invest. 2021. PMID: 33108351 Free PMC article.
Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs.
Lawson WE, Cheng DS, Degryse AL, Tanjore H, Polosukhin VV, Xu XC, Newcomb DC, Jones BR, Roldan J, Lane KB, Morrisey EE, Beers MF, Yull FE, Blackwell TS. Lawson WE, et al. Among authors: newcomb dc. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10562-7. doi: 10.1073/pnas.1107559108. Epub 2011 Jun 13. Proc Natl Acad Sci U S A. 2011. PMID: 21670280 Free PMC article.
β-catenin in the alveolar epithelium protects from lung fibrosis after intratracheal bleomycin.
Tanjore H, Degryse AL, Crossno PF, Xu XC, McConaha ME, Jones BR, Polosukhin VV, Bryant AJ, Cheng DS, Newcomb DC, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE. Tanjore H, et al. Among authors: newcomb dc. Am J Respir Crit Care Med. 2013 Mar 15;187(6):630-9. doi: 10.1164/rccm.201205-0972OC. Epub 2013 Jan 10. Am J Respir Crit Care Med. 2013. PMID: 23306543 Free PMC article.
Deficiency of gp91phox inhibits allergic airway inflammation.
Sevin CM, Newcomb DC, Toki S, Han W, Sherrill TP, Boswell MG, Zhu Z, Collins RD, Boyd KL, Goleniewska K, Huckabee MM, Blackwell TS, Peebles RS Jr. Sevin CM, et al. Among authors: newcomb dc. Am J Respir Cell Mol Biol. 2013 Sep;49(3):396-402. doi: 10.1165/rcmb.2012-0442OC. Am J Respir Cell Mol Biol. 2013. PMID: 23590311 Free PMC article.
Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner.
Dulek DE, Newcomb DC, Goleniewska K, Cephus J, Zhou W, Reiss S, Toki S, Ye F, Zaynagetdinov R, Sherrill TP, Blackwell TS, Moore ML, Boyd KL, Kolls JK, Peebles RS Jr. Dulek DE, et al. Among authors: newcomb dc. Infect Immun. 2014 Sep;82(9):3723-39. doi: 10.1128/IAI.00035-14. Epub 2014 Jun 23. Infect Immun. 2014. PMID: 24958709 Free PMC article.
Molecular analysis of idiopathic subglottic stenosis for Mycobacterium species.
Gelbard A, Katsantonis NG, Mizuta M, Newcomb D, Rotsinger J, Rousseau B, Daniero JJ, Edell ES, Ekbom DC, Kasperbauer JL, Hillel AT, Yang L, Garrett CG, Netterville JL, Wootten CT, Francis DO, Stratton C, Jenkins K, McGregor TL, Gaddy JA, Blackwell TS, Drake WP. Gelbard A, et al. Among authors: newcomb d. Laryngoscope. 2017 Jan;127(1):179-185. doi: 10.1002/lary.26097. Epub 2016 Jun 14. Laryngoscope. 2017. PMID: 27295947 Free PMC article.
Idiopathic subglottic stenosis is associated with activation of the inflammatory IL-17A/IL-23 axis.
Gelbard A, Katsantonis NG, Mizuta M, Newcomb D, Rotsinger J, Rousseau B, Daniero JJ, Edell ES, Ekbom DC, Kasperbauer JL, Hillel AT, Yang L, Garrett CG, Netterville JL, Wootten CT, Francis DO, Stratton C, Jenkins K, McGregor TL, Gaddy JA, Blackwell TS, Drake WP. Gelbard A, et al. Among authors: newcomb d. Laryngoscope. 2016 Nov;126(11):E356-E361. doi: 10.1002/lary.26098. Epub 2016 Jun 14. Laryngoscope. 2016. PMID: 27296163 Free PMC article.
PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production.
Celada LJ, Kropski JA, Herazo-Maya JD, Luo W, Creecy A, Abad AT, Chioma OS, Lee G, Hassell NE, Shaginurova GI, Wang Y, Johnson JE, Kerrigan A, Mason WR, Baughman RP, Ayers GD, Bernard GR, Culver DA, Montgomery CG, Maher TM, Molyneaux PL, Noth I, Mutsaers SE, Prele CM, Peebles RS Jr, Newcomb DC, Kaminski N, Blackwell TS, Van Kaer L, Drake WP. Celada LJ, et al. Among authors: newcomb dc. Sci Transl Med. 2018 Sep 26;10(460):eaar8356. doi: 10.1126/scitranslmed.aar8356. Sci Transl Med. 2018. PMID: 30257954 Free PMC article.
Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD.
Richmond BW, Mansouri S, Serezani A, Novitskiy S, Blackburn JB, Du RH, Fuseini H, Gutor S, Han W, Schaff J, Vasiukov G, Xin MK, Newcomb DC, Jin L, Blackwell TS, Polosukhin VV. Richmond BW, et al. Among authors: newcomb dc. Mucosal Immunol. 2021 Mar;14(2):431-442. doi: 10.1038/s41385-020-00344-9. Epub 2020 Sep 23. Mucosal Immunol. 2021. PMID: 32968197 Free PMC article.
97 results