Bolleddula J - Search Results

1

Phase I study assessing the mass balance, pharmacokinetics, and excretion of [¹⁴C]-pevonedistat, a NEDD8-activating enzyme inhibitor in patients with advanced solid tumors.

Zhou X, Sedarati F, Faller DV, Zhao D, Faessel HM, Chowdhury S, Bolleddula J, Li Y, Venkatakrishnan K, Papai Z. Zhou X, et al. Among authors: bolleddula j. Invest New Drugs. 2021 Apr;39(2):488-498. doi: 10.1007/s10637-020-01017-x. Epub 2020 Oct 22. Invest New Drugs. 2021. PMID: 33089874 Free PMC article. Clinical Trial.

2

Metabolism and Disposition of [¹⁴C]Pevonedistat, a First-in-Class NEDD8-Activating Enzyme Inhibitor, after Intravenous Infusion to Patients with Advanced Solid Tumors.

Bolleddula J, Chen H, Cohen L, Zhou X, Pusalkar S, Berger A, Sedarati F, Venkatakrishnan K, Chowdhury SK. Bolleddula J, et al. Drug Metab Dispos. 2022 Jul;50(7):989-997. doi: 10.1124/dmd.122.000842. Epub 2022 May 3. Drug Metab Dispos. 2022. PMID: 35504658

3

Carbon-carbon bond cleavage and formation reactions in drug metabolism and the role of metabolic enzymes.

Bolleddula J, Chowdhury SK. Bolleddula J, et al. Drug Metab Rev. 2015;47(4):534-57. doi: 10.3109/03602532.2015.1086781. Epub 2015 Sep 22. Drug Metab Rev. 2015. PMID: 26390887 Review.

4

Pharmacokinetics and Catabolism of [³H]TAK-164, a Guanylyl Cyclase C Targeted Antibody-Drug Conjugate.

Bolleddula J, Shah A, Shadid M, Kamali A, Smith MD, Chowdhury SK. Bolleddula J, et al. Drug Metab Dispos. 2020 Nov;48(11):1239-1245. doi: 10.1124/dmd.120.000194. Epub 2020 Aug 25. Drug Metab Dispos. 2020. PMID: 32843329

5

Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver.

Kato S, Shah A, Plesescu M, Miyata Y, Bolleddula J, Chowdhury S, Zhu X. Kato S, et al. Among authors: bolleddula j. Drug Metab Dispos. 2020 Oct;48(10):934-943. doi: 10.1124/dmd.120.000128. Epub 2020 Jul 14. Drug Metab Dispos. 2020. PMID: 32665417

6

An accelerated background subtraction algorithm for processing high-resolution MS data and its application to metabolite identification.

Shekar V, Shah A, Shadid M, Wu JT, Bolleddula J, Chowdhury S. Shekar V, et al. Among authors: bolleddula j. Bioanalysis. 2016 Aug;8(16):1693-707. doi: 10.4155/bio-2016-0101. Epub 2016 Jul 27. Bioanalysis. 2016. PMID: 27460980

7

Alternatives to rifampicin: A review and perspectives on the choice of strong CYP3A inducers for clinical drug-drug interaction studies.

Bolleddula J, Gopalakrishnan S, Hu P, Dong J, Venkatakrishnan K. Bolleddula J, et al. Clin Transl Sci. 2022 Sep;15(9):2075-2095. doi: 10.1111/cts.13357. Epub 2022 Jul 25. Clin Transl Sci. 2022. PMID: 35722783 Free PMC article. Review.

8

Current Practices, Gap Analysis, and Proposed Workflows for PBPK Modeling of Cytochrome P450 Induction: An Industry Perspective.

Hariparsad N, Ramsden D, Taskar K, Badée J, Venkatakrishnan K, Reddy MB, Cabalu T, Mukherjee D, Rehmel J, Bolleddula J, Emami Riedmaier A, Prakash C, Chanteux H, Mao J, Umehara K, Shah K, De Zwart L, Dowty M, Kotsuma M, Li M, Pilla Reddy V, McGinnity DF, Parrott N. Hariparsad N, et al. Among authors: bolleddula j. Clin Pharmacol Ther. 2022 Oct;112(4):770-781. doi: 10.1002/cpt.2503. Epub 2021 Dec 24. Clin Pharmacol Ther. 2022. PMID: 34862964

9

Catabolism of antibody drug conjugates and characterization methods.

Shadid M, Bowlin S, Bolleddula J. Shadid M, et al. Among authors: bolleddula j. Bioorg Med Chem. 2017 Jun 15;25(12):2933-2945. doi: 10.1016/j.bmc.2017.04.010. Epub 2017 Apr 11. Bioorg Med Chem. 2017. PMID: 28438386 Review.

10

Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody-Drug Conjugate in Patient-derived Xenografts.

Abu-Yousif AO, Cvet D, Gallery M, Bannerman BM, Ganno ML, Smith MD, Lai KC, Keating TA, Stringer B, Kamali A, Eng K, Koseoglu S, Zhu A, Xia CQ, Landen MS, Borland M, Robertson R, Bolleddula J, Qian MG, Fretland J, Veiby OP. Abu-Yousif AO, et al. Among authors: bolleddula j. Mol Cancer Ther. 2020 Oct;19(10):2079-2088. doi: 10.1158/1535-7163.MCT-19-1102. Epub 2020 Aug 11. Mol Cancer Ther. 2020. PMID: 32788205

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