Kosuri S - Search Results

1

Structural and functional characterization of G protein-coupled receptors with deep mutational scanning.

Jones EM, Lubock NB, Venkatakrishnan AJ, Wang J, Tseng AM, Paggi JM, Latorraca NR, Cancilla D, Satyadi M, Davis JE, Babu MM, Dror RO, Kosuri S. Jones EM, et al. Among authors: kosuri s. Elife. 2020 Oct 21;9:e54895. doi: 10.7554/eLife.54895. Elife. 2020. PMID: 33084570 Free PMC article.

2

A systematic comparison of error correction enzymes by next-generation sequencing.

Lubock NB, Zhang D, Sidore AM, Church GM, Kosuri S. Lubock NB, et al. Among authors: kosuri s. Nucleic Acids Res. 2017 Sep 6;45(15):9206-9217. doi: 10.1093/nar/gkx691. Nucleic Acids Res. 2017. PMID: 28911123 Free PMC article.

3

Multiplexed gene synthesis in emulsions for exploring protein functional landscapes.

Plesa C, Sidore AM, Lubock NB, Zhang D, Kosuri S. Plesa C, et al. Among authors: kosuri s. Science. 2018 Jan 19;359(6373):343-347. doi: 10.1126/science.aao5167. Epub 2018 Jan 4. Science. 2018. PMID: 29301959 Free PMC article.

4

A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions.

Chong R, Insigne KD, Yao D, Burghard CP, Wang J, Hsiao YE, Jones EM, Goodman DB, Xiao X, Kosuri S. Chong R, et al. Among authors: kosuri s. Mol Cell. 2019 Jan 3;73(1):183-194.e8. doi: 10.1016/j.molcel.2018.10.037. Epub 2018 Nov 29. Mol Cell. 2019. PMID: 30503770 Free PMC article.

5

A Scalable, Multiplexed Assay for Decoding GPCR-Ligand Interactions with RNA Sequencing.

Jones EM, Jajoo R, Cancilla D, Lubock NB, Wang J, Satyadi M, Chong R, de March C, Bloom JS, Matsunami H, Kosuri S. Jones EM, et al. Among authors: kosuri s. Cell Syst. 2019 Mar 27;8(3):254-260.e6. doi: 10.1016/j.cels.2019.02.009. Epub 2019 Mar 20. Cell Syst. 2019. PMID: 30904378 Free PMC article.

6

Dissection of c-AMP Response Element Architecture by Using Genomic and Episomal Massively Parallel Reporter Assays.

Davis JE, Insigne KD, Jones EM, Hastings QA, Boldridge WC, Kosuri S. Davis JE, et al. Among authors: kosuri s. Cell Syst. 2020 Jul 22;11(1):75-85.e7. doi: 10.1016/j.cels.2020.05.011. Epub 2020 Jun 29. Cell Syst. 2020. PMID: 32603702 Free article.

7

DropSynth 2.0: high-fidelity multiplexed gene synthesis in emulsions.

Sidore AM, Plesa C, Samson JA, Lubock NB, Kosuri S. Sidore AM, et al. Among authors: kosuri s. Nucleic Acids Res. 2020 Sep 18;48(16):e95. doi: 10.1093/nar/gkaa600. Nucleic Acids Res. 2020. PMID: 32692349 Free PMC article.

8

Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross.

Renganaath K, Chong R, Day L, Kosuri S, Kruglyak L, Albert FW. Renganaath K, et al. Among authors: kosuri s. Elife. 2020 Nov 12;9:e62669. doi: 10.7554/eLife.62669. Elife. 2020. PMID: 33179598 Free PMC article.

9

Multiplexed characterization of rationally designed promoter architectures deconstructs combinatorial logic for IPTG-inducible systems.

Yu TC, Liu WL, Brinck MS, Davis JE, Shek J, Bower G, Einav T, Insigne KD, Phillips R, Kosuri S, Urtecho G. Yu TC, et al. Among authors: kosuri s. Nat Commun. 2021 Jan 12;12(1):325. doi: 10.1038/s41467-020-20094-3. Nat Commun. 2021. PMID: 33436562 Free PMC article.

10

Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples.

Bloom JS, Sathe L, Munugala C, Jones EM, Gasperini M, Lubock NB, Yarza F, Thompson EM, Kovary KM, Park J, Marquette D, Kay S, Lucas M, Love T, Sina Booeshaghi A, Brandenberg OF, Guo L, Boocock J, Hochman M, Simpkins SW, Lin I, LaPierre N, Hong D, Zhang Y, Oland G, Choe BJ, Chandrasekaran S, Hilt EE, Butte MJ, Damoiseaux R, Kravit C, Cooper AR, Yin Y, Pachter L, Garner OB, Flint J, Eskin E, Luo C, Kosuri S, Kruglyak L, Arboleda VA. Bloom JS, et al. Among authors: kosuri s. Nat Biomed Eng. 2021 Jul;5(7):657-665. doi: 10.1038/s41551-021-00754-5. Epub 2021 Jul 1. Nat Biomed Eng. 2021. PMID: 34211145 Free PMC article.

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