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Page 1
Alzheimer's Retinopathy: Seeing Disease in the Eyes.
Mirzaei N, Shi H, Oviatt M, Doustar J, Rentsendorj A, Fuchs DT, Sheyn J, Black KL, Koronyo Y, Koronyo-Hamaoui M. Mirzaei N, et al. Front Neurosci. 2020 Sep 8;14:921. doi: 10.3389/fnins.2020.00921. eCollection 2020. Front Neurosci. 2020. PMID: 33041751 Free PMC article. Review.
Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina.
Shi H, Koronyo Y, Rentsendorj A, Regis GC, Sheyn J, Fuchs DT, Kramerov AA, Ljubimov AV, Dumitrascu OM, Rodriguez AR, Barron E, Hinton DR, Black KL, Miller CA, Mirzaei N, Koronyo-Hamaoui M. Shi H, et al. Among authors: mirzaei n. Acta Neuropathol. 2020 May;139(5):813-836. doi: 10.1007/s00401-020-02134-w. Epub 2020 Feb 10. Acta Neuropathol. 2020. PMID: 32043162 Free PMC article.
Parallels between retinal and brain pathology and response to immunotherapy in old, late-stage Alzheimer's disease mouse models.
Doustar J, Rentsendorj A, Torbati T, Regis GC, Fuchs DT, Sheyn J, Mirzaei N, Graham SL, Shah PK, Mastali M, Van Eyk JE, Black KL, Gupta VK, Mirzaei M, Koronyo Y, Koronyo-Hamaoui M. Doustar J, et al. Among authors: mirzaei m, mirzaei n. Aging Cell. 2020 Oct 14;19(11):e13246. doi: 10.1111/acel.13246. Online ahead of print. Aging Cell. 2020. PMID: 33090673 Free PMC article.
Retinal Vasculopathy in Alzheimer's Disease.
Shi H, Koronyo Y, Rentsendorj A, Fuchs DT, Sheyn J, Black KL, Mirzaei N, Koronyo-Hamaoui M. Shi H, et al. Among authors: mirzaei n. Front Neurosci. 2021 Sep 22;15:731614. doi: 10.3389/fnins.2021.731614. eCollection 2021. Front Neurosci. 2021. PMID: 34630020 Free PMC article. Review.
Retinal pathological features and proteome signatures of Alzheimer's disease.
Koronyo Y, Rentsendorj A, Mirzaei N, Regis GC, Sheyn J, Shi H, Barron E, Cook-Wiens G, Rodriguez AR, Medeiros R, Paulo JA, Gupta VB, Kramerov AA, Ljubimov AV, Van Eyk JE, Graham SL, Gupta VK, Ringman JM, Hinton DR, Miller CA, Black KL, Cattaneo A, Meli G, Mirzaei M, Fuchs DT, Koronyo-Hamaoui M. Koronyo Y, et al. Among authors: mirzaei m, mirzaei n. Acta Neuropathol. 2023 Apr;145(4):409-438. doi: 10.1007/s00401-023-02548-2. Epub 2023 Feb 11. Acta Neuropathol. 2023. PMID: 36773106 Free PMC article.
Alzheimer's disease pathophysiology in the Retina.
Gaire BP, Koronyo Y, Fuchs DT, Shi H, Rentsendorj A, Danziger R, Vit JP, Mirzaei N, Doustar J, Sheyn J, Hampel H, Vergallo A, Davis MR, Jallow O, Baldacci F, Verdooner SR, Barron E, Mirzaei M, Gupta VK, Graham SL, Tayebi M, Carare RO, Sadun AA, Miller CA, Dumitrascu OM, Lahiri S, Gao L, Black KL, Koronyo-Hamaoui M. Gaire BP, et al. Among authors: mirzaei n. Prog Retin Eye Res. 2024 Jul;101:101273. doi: 10.1016/j.preteyeres.2024.101273. Epub 2024 May 15. Prog Retin Eye Res. 2024. PMID: 38759947 Free article. Review.
Activation of the Wnt/β-catenin pathway represses the transcription of the β-amyloid precursor protein cleaving enzyme (BACE1) via binding of T-cell factor-4 to BACE1 promoter.
Parr C, Mirzaei N, Christian M, Sastre M. Parr C, et al. Among authors: mirzaei n. FASEB J. 2015 Feb;29(2):623-35. doi: 10.1096/fj.14-253211. Epub 2014 Nov 10. FASEB J. 2015. PMID: 25384422
In conclusion, Wnt/beta-catenin stimulation may repress BACE1 transcription via binding of TCF4 to BACE1 gene, and therefore, activation of the Wnt pathway may hold the key to new treatments of Alzheimer disease.-Parr, C., Mirzaei, N., Christian, M., and Sastre, M. …
In conclusion, Wnt/beta-catenin stimulation may repress BACE1 transcription via binding of TCF4 to BACE1 gene, and therefore, activation of …
80 results